{"eventGroups":[{"deathsNumAffected":0,"deathsNumAtRisk":4,"description":"ARM I: Patients receive 3 doses of tetanus before transplant and on days 15, and 60 post transplant.\n\nMelphalan: Given IV\n\nPeripheral Blood Stem Cell Transplantation--CD34 HSCT: Undergo autologous CD34 HSCT\n\nPeripheral Blood Stem Cell Transplantation--AHSCT: Undergo AHSCT\n\nT Cell-Depleted Hematopoietic Stem Cell Transplantation: Undergo autologous CD34 HSCT\n\nTetanus Toxoid Vaccine: Given IM","id":"EG000","otherNumAffected":4,"otherNumAtRisk":4,"seriousNumAffected":0,"seriousNumAtRisk":4,"title":"Arm I (Vaccine, CD34 Transplant, DLI)"},{"deathsNumAffected":0,"deathsNumAtRisk":4,"description":"Patients receive 3 doses of tetanus as in Arm I. Patients receive high-dose melphalan IV on day -2 and undergo AHSCT on day 0.\n\nMelphalan: Given IV\n\nPeripheral Blood Stem Cell Transplantation--AHSCT: Undergo AHSCT\n\nTetanus Toxoid Vaccine: Given IM","id":"EG001","otherNumAffected":4,"otherNumAtRisk":4,"seriousNumAffected":0,"seriousNumAtRisk":4,"title":"Arm II (Vaccine, Stem Cell Transplant)"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","stats":[{"groupId":"EG000","numAffected":4,"numAtRisk":4,"numEvents":12},{"groupId":"EG001","numAffected":4,"numAtRisk":4,"numEvents":12}],"term":"white blood cell decreased"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":4,"numEvents":6},{"groupId":"EG001","numAffected":3,"numAtRisk":4,"numEvents":8}],"term":"Lymphocyte Count Decreased"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":4,"numEvents":2},{"groupId":"EG001","numAffected":3,"numAtRisk":4,"numEvents":5}],"term":"Neutrophil Count Decreased"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Investigations","stats":[{"groupId":"EG000","numAffected":4,"numAtRisk":4,"numEvents":11},{"groupId":"EG001","numAffected":2,"numAtRisk":4,"numEvents":5}],"term":"Platelet Count Decreased"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1}],"term":"Typhlitis"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":4,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":4,"numEvents":1}],"term":"Diarrhea"},{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":4,"numEvents":1},{"groupId":"EG001","numAffected":0,"numAtRisk":4,"numEvents":0}],"term":"Anemia"}],"timeFrame":"Adverse Event Data was collected from the start of any protocol intervention to day 180 post transplant."}