{"analyses":[{"ciLowerLimit":"-375.8","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"-82.4","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"74.43","groupDescription":"Week 9 Through 24","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.0024","paramType":"LS Mean Difference","paramValue":"-229.1","statisticalMethod":"ANCOVA"},{"ciLowerLimit":"-606.3","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"-32.7","dispersionType":"STANDARD_ERROR_OF_MEAN","dispersionValue":"144.57","groupDescription":"Week 33 Through 48","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.0294","paramType":"LS Mean Difference","paramValue":"-319.5","statisticalMethod":"ANCOVA"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"54.05","value":"-2.7"},{"groupId":"OG001","spread":"68.02","value":"226.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"148"},{"groupId":"OG001","value":"74"}],"units":"Participants"}],"title":"Weeks 9-24"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"74.76","value":"-72.0"},{"groupId":"OG001","spread":"140.96","value":"247.4"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"89"},{"groupId":"OG001","value":"16"}],"units":"Participants"}],"title":"Weeks 33-48"}],"denoms":[{"counts":[{"groupId":"OG000","value":"148"},{"groupId":"OG001","value":"74"}],"units":"Participants"}],"description":"Mean change from baseline in mean serum ferritin was calculated as the difference of postbaseline mean serum ferritin (averaged over the specified timepoints) and baseline mean serum ferritin.","dispersionType":"Standard Error","groups":[{"description":"Luspatercept 1.0 mg/Kg SC on Day 1 of each 21-day treatment cycle","id":"OG000","title":"Luspatercept"},{"description":"Placebo (Volume equivalent to experimental arm) SC on Day 1 of each 21-day treatment cycle","id":"OG001","title":"Placebo"}],"paramType":"LEAST_SQUARES_MEAN","populationDescription":"All treated participants with available measurements","reportingStatus":"POSTED","timeFrame":"Baseline and Week 9 through Week 24 and Week 33 through Week 48","title":"Change From Baseline in Mean Serum Ferritin","type":"SECONDARY","unitOfMeasure":"ug/L"}