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For participants weighing \\> 100 kg, a maximum flat dose of 2 x 10\\^8 anti-CD19 CAR T cells/kg of body weight was administered.","id":"EG000","otherNumAffected":6,"otherNumAtRisk":6,"seriousNumAffected":6,"seriousNumAtRisk":6,"title":"Phase 1: 2 x 10^6 Anti-CD19 CAR T Cells/kg"},{"deathsNumAffected":17,"deathsNumAtRisk":28,"description":"Participants with r/r B-ALL received conditioning chemotherapy (fludarabine 25 mg/m\\^2 IV over 30 minutes on Day -4, Day -3, and Day -2 and cyclophosphamide 900 mg/m\\^2 IV over 60 minutes on Day -2) followed by a single infusion of brexucabtagene autoleucel CAR transduced autologous T cells administered IV at a target dose of 1 x 10\\^6 anti-CD19 CAR T cells/kg of body weight on Day 0. For participants weighing \\> 100 kg, a maximum flat dose of 1 x 10\\^8 anti-CD19 CAR T cells/kg of body weight was administered.","id":"EG001","otherNumAffected":23,"otherNumAtRisk":23,"seriousNumAffected":21,"seriousNumAtRisk":23,"title":"Phase 1: 1 x 10^6 Anti-CD19 CAR T Cells/kg"},{"deathsNumAffected":15,"deathsNumAtRisk":20,"description":"Participants with r/r B-ALL received conditioning chemotherapy (fludarabine 25 mg/m\\^2 IV over 30 minutes on Day -4, Day -3, and Day -2 and cyclophosphamide 900 mg/m\\^2 IV over 60 minutes on Day -2) followed by a single infusion of brexucabtagene autoleucel CAR transduced autologous T cells administered IV at a target dose of 0.5 x 10\\^6 anti-CD19 CAR T cells/kg of body weight on Day 0. For participants weighing \\> 100 kg, a maximum flat dose of 0.5 x 10\\^8 anti-CD19 CAR T cells/kg of body weight was administered.","id":"EG002","otherNumAffected":16,"otherNumAtRisk":16,"seriousNumAffected":12,"seriousNumAtRisk":16,"title":"Phase 1: 0.5 x 10^6 Anti-CD19 CAR T Cells/kg"},{"deathsNumAffected":39,"deathsNumAtRisk":71,"description":"Participants with r/r B-ALL received conditioning chemotherapy (fludarabine 25 mg/m\\^2 IV over 30 minutes on Day -4, Day -3, and Day -2 and cyclophosphamide 900 mg/m\\^2 IV over 60 minutes on Day -2) followed by a single infusion of brexucabtagene autoleucel CAR transduced autologous T cells administered IV at a target dose of 1 x 10\\^6 anti-CD19 CAR T cells/kg of body weight on Day 0. For participants weighing \\> 100 kg, a maximum flat dose of 1 x 10\\^8 anti-CD19 CAR T cells/kg of body weight was administered.","id":"EG003","otherNumAffected":55,"otherNumAtRisk":55,"seriousNumAffected":41,"seriousNumAtRisk":55,"title":"Phase 2: 1 x 10^6 Anti-CD19 CAR T Cells/kg"}],"frequencyThreshold":"5","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA (26.1)","stats":[{"groupId":"EG000","numAffected":3,"numAtRisk":6},{"groupId":"EG001","numAffected":14,"numAtRisk":23},{"groupId":"EG002","numAffected":4,"numAtRisk":16},{"groupId":"EG003","numAffected":29,"numAtRisk":55}],"term":"Anaemia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Blood and lymphatic system disorders","sourceVocabulary":"MedDRA 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