{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.0","upperLimit":"2.2","value":"2.0"},{"groupId":"OG001","lowerLimit":"0.5","upperLimit":"4.0","value":"1.0"},{"groupId":"OG002","lowerLimit":"2.0","upperLimit":"4.0","value":"2.0"},{"groupId":"OG003","lowerLimit":"0.5","upperLimit":"4.1","value":"1.5"},{"groupId":"OG004","lowerLimit":".5","upperLimit":"2.2","value":"1.0"},{"comment":"Individual values presented given N=2","groupId":"OG005","lowerLimit":"1.0","upperLimit":"1.1","value":"NA"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"8"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"14"},{"groupId":"OG004","value":"11"},{"groupId":"OG005","value":"2"}],"units":"Participants"}],"dispersionType":"Full Range","groups":[{"description":"INCB053914 will be self-administered orally once a day as a 100mg immediate release monotherapy dose.","id":"OG000","title":"Parts 1 and 2: INCB053914 100 mg QD"},{"description":"INCB053914 will be self-administered orally twice day as a 50mg immediate release monotherapy dose.","id":"OG001","title":"Parts 1 and 2: INCB053914 50 mg BID"},{"description":"INCB053914 will be self-administered orally twice day in as a 65mg immediate release monotherapy dose","id":"OG002","title":"Parts 1 and 2: INB053914 65 mg BID"},{"description":"INCB053914 will be self-administered orally twice day in as a 80mg immediate release monotherapy dose.","id":"OG003","title":"Parts 1 and 2: INB053914 80 mg BID"},{"description":"INCB053914 will be self-administered orally twice day as a 100mg immediate release monotherapy dose.","id":"OG004","title":"Parts 1 and 2: INB053914 100 mg BID"},{"description":"INCB053914 will be self-administered orally twice day as a 115mg immediate release monotherapy dose.","id":"OG005","title":"Parts 1 and 2: INB053914 115 mg BID"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"Cycle 1 Day 8","title":"Pharmacokinetics: Tmax of INCB053914 Monotherapy","type":"SECONDARY","unitOfMeasure":"hour"}