{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"200"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"28"}],"units":"Participants"}],"description":"Defined as the highest doses of cisplatin and berzosertib safely combined with radiation.","groups":[{"description":"Patients received different doses of M6620 (VX-970, berzosertib) by infusion in their arm weekly, cisplatin 40 mg/m2 IV weekly starting a week after M6620, and radiation therapy 70 Gy daily Monday-Friday also starting a week after M6620.","id":"OG000","title":"Dose Escalation"}],"paramType":"NUMBER","reportingStatus":"POSTED","timeFrame":"Up to 7 weeks","title":"Establish the Recommended Phase 2 Dose (RP2D)","type":"PRIMARY","unitOfMeasure":"mg/m^2"}