{"classes":[{"categories":[{"measurements":[{"comment":"The upper bounds of the confidence interval could not be calculated","groupId":"OG000","lowerLimit":"19.5","upperLimit":"NA","value":"27.6"},{"groupId":"OG001","lowerLimit":"2.0","upperLimit":"9.4","value":"5.5"},{"groupId":"OG002","lowerLimit":"3.6","upperLimit":"5.6","value":"3.7"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"38"},{"groupId":"OG001","value":"50"},{"groupId":"OG002","value":"128"}],"units":"Participants"}],"description":"Progression-free survival is defined as the time in months from the start of treatment to the date of first documented progression or death due to any cause. Progression-free survival determined by central radiological assessment per modified Response Evaluation Criteria in Solid Tumors (mRECIST), version 1.1 in patients with advanced GIST. A progressively growing tumor must meet the following criteria: a) the target lesions must be greater or equal to 2cm in size and be a new GIST active lesion or b) the target lesions must be expanding on at least 2 sequential imaging studies.","dispersionType":"95% Confidence Interval","groups":[{"description":"Patients with a PDGFRA D842V mutation, any line of treatment","id":"OG000","title":"Patients With a PDGFRA D842V Mutation"},{"description":"Patients that do not have a PDGFRA D842V mutation and have received 1 prior line of therapy","id":"OG001","title":"2L Patients Without a PDGFRA D842V Mutation"},{"description":"Patients that do not have a PDGFRA D842V mutation and have had 2 or more prior lines of therapy","id":"OG002","title":"3L Patients Without a PDGFRA D842V Mutation"}],"paramType":"MEDIAN","populationDescription":"Patients enrolled in Part 1 or Part 2 with a starting dose of 300 or 400 mg QD","reportingStatus":"POSTED","timeFrame":"Tumor assessments were performed at screening, Cycle 3 Day 1, then every 2 cycles through Cycle 13, then every 3 cycles thereafter up to approximately 4 years. Each cycle is 28 days.","title":"Progression-free Survival Per mRECIST Version 1.1","type":"SECONDARY","unitOfMeasure":"months"}