{"denomUnitsSelected":"Participants","description":"Summary statistics will be used to for describing changes across time. The time course of biomarker outcomes will be investigated graphically, by summary plots or individual patient plots. If there is suggestion of meaningful trend, methods such as linear mixed models may be used to characterize the pattern of change over time. Kaplan-Meier methodology and Cox proportional hazards models will be used to evaluate time to event endpoints.","reportingStatus":"NOT_POSTED","timeFrame":"Baseline to up to 3 years","title":"Change in Selected Biomarkers Measured in Serial Peripheral Blood","type":"OTHER_PRE_SPECIFIED"}