{"groups":[{"description":"Neupogen 16mcg/kg x 4 days Stem cell collection Drug: high dose melphalan 140 or 200 mg/m2 stem cell infusion\n\nMelphalan: Conditioning Regimen:\n\nDrug: Melphalan: 70-100 mg/m2/dose D -2, D -1 Stem Cell Transplant: D 0\n\nNeupogen: granulocyte colony-stimulating factor (G-CSF) mobilization 16mcg/kg x 4 days\n\nStem Cell Collection: collect at least 2.5 million cluster of differentiation 34 (CD34)+ stem cells\n\nStem cell infusion: infusion of previously collected autologous stem cells","id":"FG000","title":"Melphalan"},{"description":"Neupogen 16mcg/kg x 4 days Stem Cell collection drug: high-dose melphalan 140 or 200 mg/m2 drug: Bortezomib 1.0 mg/m2/dose x 4 doses stem cell infusion\n\nBortezomib: Conditioning Regimen:\n\nDrug: Bortezomib: 1.0 mg/m2/dose D -6, D -3, D +1, D + 4 Drug: Melphalan: 70-100 mg/m2/dose D -2, D -1\n\nMelphalan: Conditioning Regimen:\n\nDrug: Melphalan: 70-100 mg/m2/dose D -2, D -1 Stem Cell Transplant: D 0\n\nNeupogen: granulocyte colony-stimulating factor (G-CSF) mobilization 16mcg/kg x 4 days\n\nStem Cell Collection: collect at least 2.5 million cluster of differentiation 34 (CD34)+ stem cells\n\nStem cell infusion: infusion of previously collected autologous stem cells","id":"FG001","title":"Melphalan + Bortezomib"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"1"},{"groupId":"FG001","numSubjects":"1"}],"type":"Death"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"2"},{"groupId":"FG001","numSubjects":"1"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"1"},{"groupId":"FG001","numSubjects":"0"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"1"},{"groupId":"FG001","numSubjects":"1"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}