{"denoms":[{"counts":[{"groupId":"BG000","value":"177"},{"groupId":"BG001","value":"179"},{"groupId":"BG002","value":"179"},{"groupId":"BG003","value":"535"}],"units":"Participants"}],"groups":[{"description":"Obinutuzumab IV infusions will be administered over a total of 6 treatment cycles starting at Cycle 1 Day 1. Chlorambucil will be orally administered on Days 1 and 15 of Cycles 1 through 6. Obinutuzumab Chlorambucil","id":"BG000","title":"Obinutuzumab in Combination With Chlorambucil"},{"description":"Obinutuzumab IV infusions will be administered over a total of 6 treatment cycles starting at Cycle 2 Day 1. Acalabrutinib (ACP-196) will be orally administered starting on Cycle 1 Day 1. Daily administration of Acalabrutinib (ACP-196) will continue until disease progression or unacceptable toxicity. Acalabrutinib Obinutuzumab","id":"BG001","title":"Acalabrutinib in Combination With Obinutuzumab"},{"description":"Acalabrutinib will be orally administered on Cycle 1 Day 1 until disease progression or unacceptable toxicity. Acalabrutinib","id":"BG002","title":"Acalabrutinib Monotherapy"},{"description":"Total of all reporting groups","id":"BG003","title":"Total"}],"measures":[{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"<=18 years"},{"measurements":[{"groupId":"BG000","value":"24"},{"groupId":"BG001","value":"35"},{"groupId":"BG002","value":"28"},{"groupId":"BG003","value":"87"}],"title":"Between 18 and 65 years"},{"measurements":[{"groupId":"BG000","value":"153"},{"groupId":"BG001","value":"144"},{"groupId":"BG002","value":"151"},{"groupId":"BG003","value":"448"}],"title":">=65 years"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Age, Categorical","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"71"},{"groupId":"BG001","value":"68"},{"groupId":"BG002","value":"68"},{"groupId":"BG003","value":"207"}],"title":"Female"},{"measurements":[{"groupId":"BG000","value":"106"},{"groupId":"BG001","value":"111"},{"groupId":"BG002","value":"111"},{"groupId":"BG003","value":"328"}],"title":"Male"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Sex: Female, Male","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"11"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"11"},{"groupId":"BG003","value":"24"}],"title":"Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"156"},{"groupId":"BG001","value":"169"},{"groupId":"BG002","value":"156"},{"groupId":"BG003","value":"481"}],"title":"Not Hispanic or Latino"},{"measurements":[{"groupId":"BG000","value":"10"},{"groupId":"BG001","value":"8"},{"groupId":"BG002","value":"12"},{"groupId":"BG003","value":"30"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Ethnicity (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"1"}],"title":"American Indian or Alaska Native"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"3"}],"title":"Asian"},{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"1"}],"title":"Native Hawaiian or Other Pacific Islander"},{"measurements":[{"groupId":"BG000","value":"4"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"4"},{"groupId":"BG003","value":"13"}],"title":"Black or African American"},{"measurements":[{"groupId":"BG000","value":"165"},{"groupId":"BG001","value":"164"},{"groupId":"BG002","value":"170"},{"groupId":"BG003","value":"499"}],"title":"White"},{"measurements":[{"groupId":"BG000","value":"0"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"0"}],"title":"More than one race"},{"measurements":[{"groupId":"BG000","value":"6"},{"groupId":"BG001","value":"7"},{"groupId":"BG002","value":"5"},{"groupId":"BG003","value":"18"}],"title":"Unknown or Not Reported"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Race (NIH/OMB)","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"5"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"13"}]}],"title":"Belgium"},{"categories":[{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"1"},{"groupId":"BG003","value":"7"}]}],"title":"France"},{"categories":[{"measurements":[{"groupId":"BG000","value":"3"},{"groupId":"BG001","value":"1"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"7"}]}],"title":"Germany"},{"categories":[{"measurements":[{"groupId":"BG000","value":"11"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"5"},{"groupId":"BG003","value":"25"}]}],"title":"Italy"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"13"}]}],"title":"Spain"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"3"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"7"}]}],"title":"Sweden"},{"categories":[{"measurements":[{"groupId":"BG000","value":"12"},{"groupId":"BG001","value":"16"},{"groupId":"BG002","value":"17"},{"groupId":"BG003","value":"45"}]}],"title":"United Kingdom"},{"categories":[{"measurements":[{"groupId":"BG000","value":"4"},{"groupId":"BG001","value":"5"},{"groupId":"BG002","value":"5"},{"groupId":"BG003","value":"14"}]}],"title":"Brazil"},{"categories":[{"measurements":[{"groupId":"BG000","value":"2"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"3"},{"groupId":"BG003","value":"5"}]}],"title":"Chile"},{"categories":[{"measurements":[{"groupId":"BG000","value":"1"},{"groupId":"BG001","value":"0"},{"groupId":"BG002","value":"0"},{"groupId":"BG003","value":"1"}]}],"title":"Colombia"},{"categories":[{"measurements":[{"groupId":"BG000","value":"7"},{"groupId":"BG001","value":"8"},{"groupId":"BG002","value":"7"},{"groupId":"BG003","value":"22"}]}],"title":"Canada"},{"categories":[{"measurements":[{"groupId":"BG000","value":"54"},{"groupId":"BG001","value":"56"},{"groupId":"BG002","value":"63"},{"groupId":"BG003","value":"173"}]}],"title":"United States"},{"categories":[{"measurements":[{"groupId":"BG000","value":"17"},{"groupId":"BG001","value":"26"},{"groupId":"BG002","value":"15"},{"groupId":"BG003","value":"58"}]}],"title":"Hungary"},{"categories":[{"measurements":[{"groupId":"BG000","value":"9"},{"groupId":"BG001","value":"2"},{"groupId":"BG002","value":"6"},{"groupId":"BG003","value":"17"}]}],"title":"Lithuania"},{"categories":[{"measurements":[{"groupId":"BG000","value":"14"},{"groupId":"BG001","value":"20"},{"groupId":"BG002","value":"25"},{"groupId":"BG003","value":"59"}]}],"title":"Poland"},{"categories":[{"measurements":[{"groupId":"BG000","value":"9"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"8"},{"groupId":"BG003","value":"26"}]}],"title":"Australia"},{"categories":[{"measurements":[{"groupId":"BG000","value":"8"},{"groupId":"BG001","value":"4"},{"groupId":"BG002","value":"5"},{"groupId":"BG003","value":"17"}]}],"title":"New Zealand"},{"categories":[{"measurements":[{"groupId":"BG000","value":"10"},{"groupId":"BG001","value":"9"},{"groupId":"BG002","value":"7"},{"groupId":"BG003","value":"26"}]}],"title":"Israel"}],"paramType":"COUNT_OF_PARTICIPANTS","title":"Region of Enrollment","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"17"},{"groupId":"BG001","value":"21"},{"groupId":"BG002","value":"19"},{"groupId":"BG003","value":"57"}],"title":"Yes"},{"measurements":[{"groupId":"BG000","value":"160"},{"groupId":"BG001","value":"158"},{"groupId":"BG002","value":"160"},{"groupId":"BG003","value":"478"}],"title":"No"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"IXRS Randomization Stratification Factor: Presence of 17p Deletion","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"168"},{"groupId":"BG001","value":"169"},{"groupId":"BG002","value":"167"},{"groupId":"BG003","value":"504"}],"title":"0-1 (0=Fully Active; 1 =Restricted in Physically Strenuous Activity)"},{"measurements":[{"groupId":"BG000","value":"9"},{"groupId":"BG001","value":"10"},{"groupId":"BG002","value":"12"},{"groupId":"BG003","value":"31"}],"title":"2 (2=Ambulatory and capable of all selfcare but unable to carry out any work activities)"}]}],"description":"Lower Grade is Better. 0=Fully active; 1=Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature; 2=Ambulatory and capable of all selfcare but unable to carry out any work activities;","paramType":"COUNT_OF_PARTICIPANTS","title":"IXRS Randomization Stratification Factor: ECOG Performance Status","unitOfMeasure":"Participants"},{"classes":[{"categories":[{"measurements":[{"groupId":"BG000","value":"103"},{"groupId":"BG001","value":"104"},{"groupId":"BG002","value":"105"},{"groupId":"BG003","value":"312"}],"title":"North America and West Europe"},{"measurements":[{"groupId":"BG000","value":"74"},{"groupId":"BG001","value":"75"},{"groupId":"BG002","value":"74"},{"groupId":"BG003","value":"223"}],"title":"Other"}]}],"paramType":"COUNT_OF_PARTICIPANTS","title":"IXRS Randomization Stratification Factor: Geographic Region","unitOfMeasure":"Participants"}],"populationDescription":"Analysis was performed on intent-to-treat (ITT) population, which included all randomized participants grouped according to assigned treatment."}