{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"21.3","value":"61.8"},{"groupId":"OG001","spread":"42.9","value":"85.0"},{"groupId":"OG002","spread":"29.4","value":"81.7"},{"groupId":"OG003","spread":"184","value":"234"},{"groupId":"OG004","spread":"201","value":"92.3"},{"groupId":"OG005","spread":"33.7","value":"48.3"},{"groupId":"OG006","spread":"127","value":"130"},{"groupId":"OG007","spread":"135","value":"95.5"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"4"},{"groupId":"OG002","value":"4"},{"groupId":"OG003","value":"4"},{"groupId":"OG004","value":"14"},{"groupId":"OG005","value":"11"},{"groupId":"OG006","value":"7"},{"groupId":"OG007","value":"48"}],"units":"Participants"}],"description":"Cl/F is the apparent oral dose clearance measured at steady state (Day 15). Study drug was administered with 240 mL of water.","dispersionType":"Standard Deviation","groups":[{"description":"INCB054329 Monotherapy","id":"OG000","title":"INCB054329 Monotherapy - 15 mg QD"},{"description":"INCB054329 Monotherapy","id":"OG001","title":"INCB054329 Monotherapy - 15 mg BID"},{"description":"INCB054329 Monotherapy","id":"OG002","title":"INCB054329 Monotherapy - 22.5 mg BID"},{"description":"INCB054329 Monotherapy","id":"OG003","title":"INCB054329 Monotherapy - 30 mg QD"},{"description":"INCB054329 Monotherapy","id":"OG004","title":"INCB054329 Monotherapy - 20 mg BID"},{"description":"INCB054329 Monotherapy","id":"OG005","title":"INCB054329 Monotherapy - 22.5 mg QD"},{"description":"INCB054329 Monotherapy","id":"OG006","title":"INCB054329 Monotherapy - 25 mg BID"},{"description":"INCB054329 Monotherapy","id":"OG007","title":"INCB054329 Monotherapy - Overall Dosing Regimen"}],"paramType":"MEAN","populationDescription":"All enrolled patients who received at least 1 dose of study medication and provided at least 1 plasma sample were included.","reportingStatus":"POSTED","timeFrame":"Summary of steady-state PK parameters by dosing regimen at Day 15","title":"Cl/F Analysis of INCB054329","type":"SECONDARY","unitOfMeasure":"L/h"}