{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"3.5","value":"7.3"},{"groupId":"OG001","spread":"3.7","value":"7.4"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"13"}],"units":"Participants"}],"title":"Baseline Anxiety Score"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.3","value":"4.4"},{"groupId":"OG001","spread":"3.7","value":"5.2"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"11"},{"groupId":"OG001","value":"11"}],"units":"Participants"}],"title":"4-Week Anxiety Score"}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"13"}],"units":"Participants"}],"description":"This measure will be assessed using the Hospital Anxiety and Depression Scale (HADS). The HADS scale includes fourteen 4-response Likert-scale questions graded 0 to 3. Seven questions are specific to depression; 7 questions are specific to anxiety. The score is the total of the responses in their respective categories. Lower scores indicated less depression and/or anxiety. Scores 0-7 indicate normal status; scores 8-10 suggest borderline abnormal status; and scores 11-21 indicate abnormal status. Only anxiety scores are presented.","dispersionType":"Standard Deviation","groups":[{"description":"Patient's randomized to the Propranolol arm will be starting 7 days prior to transplant and continuing through 28 days post-transplant. Propranolol will start at 20mg twice daily and will be titrated to 40mg twice daily as tolerated. Both groups will come back to the hospital weekly in order to assess items such as patient's level of anxiety, depression, your adherence, and also to monitor for side effects. The patient's will complete questionnaires during your visit. These will take approximately 15 minutes to complete. This will continue for up to 7 total weeks for patient's on the Propranolol arm.\n\nPropranolol","id":"OG000","title":"Propranolol"},{"description":"Both groups will come back to the hospital weekly in order to assess items such as patient's level of anxiety, depression, your adherence, and also to monitor for side effects. The patient's will complete questionnaires during your visit. These will take approximately 15 minutes to complete. This will continue for 6 total weeks for patient's on the control arm.","id":"OG001","title":"Control Arm"}],"paramType":"MEAN","populationDescription":"One propranolol subject was discontinued due to symptomatic hypotension. Two control subjects were discontinued doe to initiation of beta-blocker therapy for cardiac arrhythmia.","reportingStatus":"POSTED","timeFrame":"Baseline and 4 weeks","title":"Patient-reported Depression and Anxiety Scores","type":"SECONDARY","unitOfMeasure":"units on a scale"}