{"analyses":[{"groupDescription":"Variation in serum levels of FSH at week 1","groupIds":["OG000"],"nonInferiorityType":"OTHER","pValue":"<0.05","statisticalMethod":"Dunn Test"},{"groupDescription":"Variation in serum levels of FSH at week 3","groupIds":["OG000"],"nonInferiorityType":"OTHER","pValue":"<0.05","statisticalMethod":"Dunn Test"},{"groupDescription":"Variation in serum levels of FSH at week 8","groupIds":["OG000"],"nonInferiorityType":"OTHER","pValue":">0.05","statisticalMethod":"Dunn Test"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-11.6","upperLimit":"2.6","value":"-4.8"},{"groupId":"OG001","lowerLimit":"-7.8","upperLimit":"7.3","value":"4.2"}]}],"title":"change from baseline to week 1"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-12.0","upperLimit":"3.5","value":"-4.2"},{"groupId":"OG001","lowerLimit":"-4.0","upperLimit":"2.3","value":"-0.9"}]}],"title":"change from baseline to week 3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"-10.1","upperLimit":"7.9","value":"-2.6"},{"groupId":"OG001","lowerLimit":"-11.8","upperLimit":"9","value":"5.2"}]}],"title":"change from baseline to week 8"}],"denoms":[{"counts":[{"groupId":"OG000","value":"50"},{"groupId":"OG001","value":"11"}],"units":"Participants"}],"description":"Change from Baseline (mean screening-baseline) to Week 1, Week 3 and Week 8 in Serum Levels of Follicle Stimulating Hormone (FSH) compare to natural physiological variability ( screening-baseline variation)","dispersionType":"Inter-Quartile Range","groups":[{"description":"Route: Vaginal. Administration by an applicator inserted deep inside the vagina Dose: 1 g of gel, containing 50 Mcg of estriol Dosage schedule: Weeks 1-3: single daily application Weeks 4-12: twice weekly administration\n\nestriol: 0.005% estriol vaginal gel","id":"OG000","title":"0.005% Estriol Vaginal Gel"},{"description":"Route: Vaginal. Administration by an applicator inserted deep inside the vagina Dose: 1 g of gel. Dosage schedule: Weeks 1-3: single daily application Weeks 4-12: twice weekly administration\n\nPlacebo: placebo vaginal gel","id":"OG001","title":"Placebo Vaginal Gel"}],"paramType":"MEAN","populationDescription":"postmenopausal women","reportingStatus":"POSTED","timeFrame":"Change from baseline to week 1, week 3 and week 8","title":"Variation in Serum Levels of FSH at Week 1, Week 3 and Week 8","type":"SECONDARY","unitOfMeasure":"mIU/ml"}