{"groups":[{"description":"Nivolumab 3 mg/kg IV q2 wks and Ipilimumab placebo IV q3 wks for 4 doses then q12 wks starting at Wk 24","id":"FG000","title":"Nivolumab 3 mg/kg"},{"description":"Ipilimumab 10 mg/kg IV q3 wks for 4 doses then q12 wks starting at Wk 24 and Nivolumab placebo IV q2 wks","id":"FG001","title":"Ipilimumab 10 mg/kg"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"1"},{"groupId":"FG001","numSubjects":"0"}],"type":"Participant withdrew consent"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"453"},{"groupId":"FG001","numSubjects":"453"}],"comment":"Started=Randomized","type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"452"},{"groupId":"FG001","numSubjects":"453"}],"comment":"completed=treated","type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"1"},{"groupId":"FG001","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Pre-Treatment Period"},{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"121"},{"groupId":"FG001","numSubjects":"100"}],"type":"Disease progression"},{"reasons":[{"groupId":"FG000","numSubjects":"41"},{"groupId":"FG001","numSubjects":"208"}],"type":"Study drug toxicity"},{"reasons":[{"groupId":"FG000","numSubjects":"5"},{"groupId":"FG001","numSubjects":"5"}],"type":"Adverse Event (AE) unrelated to study drug"},{"reasons":[{"groupId":"FG000","numSubjects":"5"},{"groupId":"FG001","numSubjects":"9"}],"type":"Participant request to stop treatment"},{"reasons":[{"groupId":"FG000","numSubjects":"2"},{"groupId":"FG001","numSubjects":"3"}],"type":"Participant withdrew consent"},{"reasons":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"1"}],"type":"Poor/non-compliance"},{"reasons":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"1"}],"type":"Participant no longer meets study criteria"},{"reasons":[{"groupId":"FG000","numSubjects":"3"},{"groupId":"FG001","numSubjects":"3"}],"type":"Other reasons"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"452"},{"groupId":"FG001","numSubjects":"453"}],"comment":"Started=Treated","type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"275"},{"groupId":"FG001","numSubjects":"123"}],"comment":"Completed=Finished the treatment period","type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"177"},{"groupId":"FG001","numSubjects":"330"}],"type":"NOT COMPLETED"}],"title":"Treatment Period"}],"preAssignmentDetails":"906 participants randomized and 905 treated. Reason for not treated: 1 participant withdrew consent."}