{"analyses":[{"ciLowerLimit":"-0.54","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"13.90","groupDescription":"1-Year ITT-WT Population","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"SUPERIORITY","pValue":"0.0697","paramType":"Difference in Event Free Rate","paramValue":"6.68","statisticalMethod":"Z-test"},{"ciLowerLimit":"0.70","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"18.73","groupDescription":"2-Year ITT-WT Population","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"SUPERIORITY","pValue":"0.0347","paramType":"Difference in Event Free Rate","paramValue":"9.71","statisticalMethod":"Z-test"},{"ciLowerLimit":"-1.51","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"21.29","groupDescription":"1-Year Teff-high WT Population","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"SUPERIORITY","pValue":"0.0890","paramType":"Difference in Event Free Rate","paramValue":"9.89","statisticalMethod":"Z-test"},{"ciLowerLimit":"-3.17","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"23.84","groupDescription":"2-Year Teff-high WT Population","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"OTHER","pValue":"0.1336","paramType":"Difference in Event Free Rate","paramValue":"10.34","statisticalMethod":"Z-test"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"61.28","upperLimit":"75.98","value":"68.63"},{"groupId":"OG001","lowerLimit":"50.03","upperLimit":"67.45","value":"58.74"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"105"},{"groupId":"OG001","value":"71"}],"units":"Participants"}],"title":"1-Year Teff-high WT Population"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"62.41","upperLimit":"72.22","value":"67.32"},{"groupId":"OG001","lowerLimit":"55.34","upperLimit":"65.93","value":"60.63"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"235"},{"groupId":"OG001","value":"196"}],"units":"Participants"}],"title":"1-Year ITT-WT Population"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"43.12","upperLimit":"60.94","value":"52.03"},{"groupId":"OG001","lowerLimit":"31.55","upperLimit":"51.85","value":"41.70"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"21"},{"groupId":"OG001","value":"15"}],"units":"Participants"}],"title":"2-Year Teff-high WT Population"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"36.94","upperLimit":"49.90","value":"43.42"},{"groupId":"OG001","lowerLimit":"27.44","upperLimit":"39.98","value":"33.71"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"34"},{"groupId":"OG001","value":"29"}],"units":"Participants"}],"title":"2-Year ITT-WT Population"}],"denoms":[{"counts":[{"groupId":"OG000","value":"235"},{"groupId":"OG001","value":"196"}],"units":"Participants"}],"description":"OS at 1- and 2-year landmark timepoints in Teff-high WT population and ITT-WT population.","dispersionType":"95% Confidence Interval","groups":[{"description":"Participants received IV infusion of atezolizumab and bevacizumab on Day 1 of each 21-day cycle followed by IV infusion of paclitaxel and carboplatin on Day 1 of each 21-day cycle for 4 or 6 cycles or until loss of clinical benefit whichever occurs first, during induction treatment phase. Participants received IV infusion of atezolizumab until loss of clinical benefit and bevacizumab until progressive disease, unacceptable toxicity, or death during maintenance treatment phase.","id":"OG000","title":"Arm B (Atezolizumab+Bevacizumab+Paclitaxel + Carboplatin)"},{"description":"Participants received IV infusion of bevacizumab on Day 1 of each 21-day cycle followed by IV infusion of paclitaxel and carboplatin on Day 1 of each 21-day cycle for 4 or 6 cycles or loss of clinical benefit whichever occurs first, during induction treatment phase. Participants received IV infusion of bevacizumab during maintenance treatment phase until progressive disease, unacceptable toxicity, or death.","id":"OG001","title":"Arm C (Bevacizumab+Paclitaxel+Carboplatin)"}],"paramType":"NUMBER","populationDescription":"Teff-high WT population is defined as the Teff-high population excluding patients with an activating EGFR mutation or ALK translocation. ITT-WT population is defined as the ITT population excluding patients with an activating EGFR mutation or ALK translocation.","reportingStatus":"POSTED","timeFrame":"Baseline to 2 years or death, whichever occurs first.","title":"OS Rates at Years 1 and 2 in Arm B Versus Arm C","type":"SECONDARY","unitOfMeasure":"Percentage"}