{"analyses":[{"ciLowerLimit":"0.406","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.675","groupDescription":"ITT-WT","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"SUPERIORITY","pValue":"<.0001","paramType":"Hazard Ratio (HR)","paramValue":"0.523","statisticalMethod":"Log Rank"},{"ciLowerLimit":"0.283","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.624","groupDescription":"Teff-high WT","groupIds":["OG000","OG001"],"nonInferiorityComment":"Stratified Analysis","nonInferiorityType":"SUPERIORITY","pValue":"<.0001","paramType":"Hazard Ratio (HR)","paramValue":"0.420","statisticalMethod":"Log Rank"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"9.7","upperLimit":"15.7","value":"11.2"},{"groupId":"OG001","lowerLimit":"4.9","upperLimit":"7.0","value":"5.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"106"},{"groupId":"OG001","value":"68"}],"units":"Participants"}],"title":"Teff high-WT Population"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"6.9","upperLimit":"11.4","value":"9.0"},{"groupId":"OG001","lowerLimit":"5.1","upperLimit":"6.5","value":"5.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"224"},{"groupId":"OG001","value":"159"}],"units":"Participants"}],"title":"ITT-WT Population"}],"denoms":[{"counts":[{"groupId":"OG000","value":"224"},{"groupId":"OG001","value":"159"}],"units":"Participants"}],"description":"DOR, as determined by investigator according to RECIST v1.1 in Arm B versus Arm C in the Teff high-WT population and the ITT-WT population.","dispersionType":"95% Confidence Interval","groups":[{"description":"Participants received IV infusion of atezolizumab and bevacizumab on Day 1 of each 21-day cycle followed by IV infusion of paclitaxel and carboplatin on Day 1 of each 21-day cycle for 4 or 6 cycles or until loss of clinical benefit whichever occurs first, during induction treatment phase. Participants received IV infusion of atezolizumab until loss of clinical benefit and bevacizumab until progressive disease, unacceptable toxicity, or death during maintenance treatment phase.","id":"OG000","title":"Arm B (Atezolizumab+Bevacizumab+Paclitaxel + Carboplatin)"},{"description":"Participants received IV infusion of bevacizumab on Day 1 of each 21-day cycle followed by IV infusion of paclitaxel and carboplatin on Day 1 of each 21-day cycle for 4 or 6 cycles or loss of clinical benefit whichever occurs first, during induction treatment phase. Participants received IV infusion of bevacizumab during maintenance treatment phase until progressive disease, unacceptable toxicity, or death.","id":"OG001","title":"Arm C (Bevacizumab+Paclitaxel+Carboplatin)"}],"paramType":"MEDIAN","populationDescription":"Teff-high WT population is defined as the Teff-high population excluding patients with an activating EGFR mutation or ALK translocation. ITT-WT population is defined as the ITT population excluding patients with an activating EGFR mutation or ALK translocation.","reportingStatus":"POSTED","timeFrame":"Baseline until disease progression or death, whichever occurs first (up to approximately 29 months)","title":"Duration of Response (DOR), as Determined By Investigator in Arm B Versus Arm C","type":"SECONDARY","unitOfMeasure":"Months"}