{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"986","value":"2465"},{"groupId":"OG001","spread":"1127","value":"2687"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"},{"groupId":"OG001","value":"19"}],"units":"Participants"}],"description":"Cmax is the maximum observed plasma concentration of metformin alone or in combination with erdafitinib","dispersionType":"Standard Deviation","groups":[{"description":"Participants received single dose of metformin 1000 mg tablet, orally, once daily, starting from Day -1 through Day 14 of Cycle 1 (each cycle length=28 days).","id":"OG000","title":"DDI Study: Metformin 1000 mg Alone"},{"description":"Participants received single dose of metformin 1000 mg tablet, orally, once daily, starting from Day -1 through Day 14 of Cycle 1 along with erdafitinib 8 mg starting from Day 1 up to Day 15 of Cycle 1 (each cycle length=28 days).","id":"OG001","title":"DDI Study: Metformin 1000 mg + Erdafitinib 8 mg"}],"paramType":"MEAN","populationDescription":"Pharmacokinetic analysis set included all participants who received at least 1 dose of study drug and had at least 1 sample collected during treatment to determine the drug concentration. Here 'N' (number of participants analyzed) signifies number of participants who were evaluable for this outcome measure.","reportingStatus":"POSTED","timeFrame":"Cycle 1 Day -1 (predose) up to Day 14 post dose (each cycle length=28 days)","title":"Drug-Drug Interaction (DDI) Substudy: Maximum Observed Plasma Concentration (Cmax) of Metformin Alone or in Combination With Erdafitinib","type":"PRIMARY","unitOfMeasure":"ng/mL"}