{"description":"All adverse events reported by study participants from the time of study drug administration through 30 days after the final treatment, whether or not they are related to the study intervention.\n\nParticipants filled out a symptom diary for each treatment cycle completed. 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enrolled in this cohort will receive 2 five day cycles of Artesunate suppositories prior to therapeutic resection of their lesion (if clinically indicated).\n\nArtesunate Suppositories","id":"EG002","otherNumAffected":8,"otherNumAtRisk":10,"seriousNumAffected":0,"seriousNumAtRisk":10,"title":"200 mg Artesunate Suppositories,2 Cycles"},{"deathsNumAffected":0,"deathsNumAtRisk":8,"description":"Subjects enrolled in this cohort will receive 3 five day cycles of Artesunate suppositories prior to therapeutic resection of their lesion (if clinically indicated).\n\nArtesunate Suppositories","id":"EG003","otherNumAffected":8,"otherNumAtRisk":8,"seriousNumAffected":0,"seriousNumAtRisk":8,"title":"200 mg Artesunate Suppositories,3 Cycles"}],"frequencyThreshold":"0","otherEvents":[{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"CTCAE 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(4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Abdominal pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":9,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Diarrhea"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"Loss in appetite","organSystem":"Gastrointestinal disorders","sourceVocabulary":"CTCAE 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(4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":2}],"term":"Chills"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Fatigue"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":9,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Fever"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"General disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"Flu-like symptoms"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"bacterial or yeast infections","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":2,"numAtRisk":9,"numEvents":2},{"groupId":"EG002","numAffected":4,"numAtRisk":10,"numEvents":4},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":2}],"term":"Vaginal infection"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Infections and infestations","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"Urinary tract infection"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Musculoskeletal and connective tissue disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":1,"numAtRisk":9,"numEvents":1},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Vaginal twitching"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"sensation of movement, unsteadiness","organSystem":"Nervous system disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":2},{"groupId":"EG001","numAffected":2,"numAtRisk":9,"numEvents":6},{"groupId":"EG002","numAffected":3,"numAtRisk":10,"numEvents":5},{"groupId":"EG003","numAffected":3,"numAtRisk":8,"numEvents":3}],"term":"Dizziness"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Nervous system disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":2},{"groupId":"EG001","numAffected":5,"numAtRisk":9,"numEvents":9},{"groupId":"EG002","numAffected":3,"numAtRisk":10,"numEvents":3},{"groupId":"EG003","numAffected":2,"numAtRisk":8,"numEvents":2}],"term":"Headache"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Anxiety"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Psychiatric disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Insomnia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"painful urination","organSystem":"Renal and urinary disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"Cystitis noninfective"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":2,"numAtRisk":3,"numEvents":5},{"groupId":"EG001","numAffected":1,"numAtRisk":9,"numEvents":3},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":2,"numAtRisk":8,"numEvents":2}],"term":"Uterine cramping"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"Dyspareunia"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"pelvic pain"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":3,"numAtRisk":9,"numEvents":3},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":4},{"groupId":"EG003","numAffected":3,"numAtRisk":8,"numEvents":4}],"term":"Vaginal discharge"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"pruritus due to dryness","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":1,"numAtRisk":3,"numEvents":1},{"groupId":"EG001","numAffected":1,"numAtRisk":9,"numEvents":1},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":2},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"Vaginal dryness"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"light spotting","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":3,"numAtRisk":9,"numEvents":3},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"Vaginal hemorrhage"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":2}],"term":"vaginal inflammation"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Reproductive system and breast disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":4,"numAtRisk":9,"numEvents":5},{"groupId":"EG002","numAffected":4,"numAtRisk":10,"numEvents":4},{"groupId":"EG003","numAffected":4,"numAtRisk":8,"numEvents":7}],"term":"vaginal pain/burning"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"eczema","organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":0,"numAtRisk":10,"numEvents":0},{"groupId":"EG003","numAffected":1,"numAtRisk":8,"numEvents":1}],"term":"rash"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","notes":"body itching","organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":0,"numAtRisk":9,"numEvents":0},{"groupId":"EG002","numAffected":1,"numAtRisk":10,"numEvents":1},{"groupId":"EG003","numAffected":0,"numAtRisk":8,"numEvents":0}],"term":"pruritus"},{"assessmentType":"SYSTEMATIC_ASSESSMENT","organSystem":"Skin and subcutaneous tissue disorders","sourceVocabulary":"CTCAE (4.0)","stats":[{"groupId":"EG000","numAffected":0,"numAtRisk":3,"numEvents":0},{"groupId":"EG001","numAffected":3,"numAtRisk":9,"numEvents":3},{"groupId":"EG002","numAffected":5,"numAtRisk":10,"numEvents":5},{"groupId":"EG003","numAffected":6,"numAtRisk":8,"numEvents":11}],"term":"Vaginal pruritus"}],"timeFrame":"41 weeks"}