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Participants who did not achieve a PASI75 response at Week 16 escaped to CZP 400 mg Q2W.\n\nParticipants who received unblinded CZP 400 mg Q2W for 16 weeks and did not achieve a PASI50 response were withdrawn from the study. Participants could enter a 96-week open-label extension period after completing the Maintenance Period and receive CZP under certain conditions.","id":"FG001","title":"Etanercept"},{"description":"CZP 400 mg injections at Weeks 0, 2, 4, followed by CZP 200 mg every 2 weeks (Q2W) from Week 6 to Week 14. Treatment received from Week 16-48 is based on initial treatment and response to treatment:\n\n•PASI75 responders at Week 16 were re-randomized to receive either CZP 200 mg Q2W or CZP 400 mg every 4 weeks (Q4W); with Placebo administered on alternate dosing weeks to maintain the blind) Or Placebo Q2W. Participants who did not achieve a PASI75 response at Week 16 were removed from blinded study medication and escaped to CZP 400 mg Q2W.\n\nParticipants who received unblinded CZP 400 mg Q2W for 16 weeks and did not achieve a PASI50 response were withdrawn from the study. Participants could enter a 96-week open-label extension period after completing the Maintenance Period and receive CZP under certain conditions.","id":"FG002","title":"CZP 200 mg Q2W"},{"description":"CZP 400 mg injections every 2 weeks (Q2W) through Week 14. Treatment received from Week 16-48 is based on initial treatment and response to treatment:\n\n•PASI75 responders at Week 16 were re-randomized to CZP 200 mg Q2W or CZP 400 mg Q2W or Placebo Q2W. Participants who did not achieve a PASI75 response at Week 16 were removed from blinded study medication and escaped to CZP 400 mg Q2W.\n\nParticipants who received unblinded CZP 400 mg Q2W for 16 weeks and did not achieve a PASI50 response were withdrawn from the study. Participants could enter a 96-week open-label extension period after completing the Maintenance Period and receive CZP under certain conditions.","id":"FG003","title":"CZP 400 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the Placebo arm, who achieved a PASI75 response at Week 16 and continued to receive blinded Placebo in the Maintenance Period (Week 16 to Week 48).","id":"FG004","title":"Placebo/Placebo Q2W"},{"description":"This arm consisted of participants initially randomized in the Etanercept arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded Placebo in the Maintenance Period (Week 16 to Week 48).","id":"FG005","title":"Etanercept/Placebo Q2W"},{"description":"This arm consisted of participants initially randomized in the Etanercept arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded CZP 200 mg Q2W in the Maintenance Period (Week 16 to Week 48).","id":"FG006","title":"Etanercept/CZP 200 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 200 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded Placebo in the Maintenance Period (Week 16 to Week 48).","id":"FG007","title":"CZP 200 mg Q2W/Placebo Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 200 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded CZP 200 mg Q2W in the Maintenance Period (Week 16 to Week 48).","id":"FG008","title":"CZP 200 mg Q2W/CZP 200 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 200 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded CZP 400 mg Q4W in the Maintenance Period (Week 16 to Week 48).","id":"FG009","title":"CZP 200 mg Q2W/CZP 400 mg Q4W"},{"description":"This arm consisted of participants initially randomized in the CZP 400 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded Placebo in the Maintenance Period (Week 16 to Week 48).","id":"FG010","title":"CZP 400 mg Q2W/Placebo Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 400 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded CZP 200 mg Q2W in the Maintenance Period (Week 16 to Week 48).","id":"FG011","title":"CZP 400 mg Q2W/CZP 200 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 400 mg arm, who achieved a PASI75 response at Week 16 and were re-randomized to receive blinded CZP 400 mg Q2W in the Maintenance Period (Week 16 to Week 48).","id":"FG012","title":"CZP 400 mg Q2W/CZP 400 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the Placebo arm, who did not achieve a PASI75 response at Week 16 escaped from the blinded treatment and received CZP 400 mg every two weeks. Participants who did not achieve PASI50 after 16 weeks of unblinded treatment were withdrawn from the study.","id":"FG013","title":"Placebo Q2W/Escape CZP 400 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the Etanercept arm, who did not achieve a PASI75 response at Week 16 escaped from the treatment and received CZP 400 mg every two weeks. Participants who did not achieve PASI50 after 16 weeks of unblinded treatment were withdrawn from the study.","id":"FG014","title":"Etanercept/Escape CZP 400 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 200 mg arm, who did not achieve a PASI75 response at Week 16 escaped from the blinded treatment and received CZP 400 mg every two weeks. Participants who did not achieve PASI50 after 16 weeks of unblinded treatment were withdrawn from the study.","id":"FG015","title":"CZP 200 mg Q2W/Escape CZP 400 mg Q2W"},{"description":"This arm consisted of participants initially randomized in the CZP 400 mg arm, who did not achieve a PASI75 response at Week 16 escaped from the blinded treatment and received CZP 400 mg every two weeks. Participants who did not achieve PASI50 after 16 weeks of unblinded treatment were withdrawn from the study.","id":"FG016","title":"CZP 400 mg Q2W/Escape CZP 400 mg Q2W"},{"description":"This arm consisted of participants from the Placebo-controlled Maintenance Period, who achieved PASI50 response (had no relapse) at Week 48 and entered the 96-Weeks OLE Period receiving CZP 200 mg Q2W.","id":"FG017","title":"Placebo/CZP 200 mg Q2W OLE"},{"description":"This arm consisted of participants who received CZP 200 mg Q2W in the Maintenance Period, who achieved a PASI50 response (had no relapse) at Week 48 and entered OLE.","id":"FG018","title":"CZP 200 mg Q2W/CZP 200 mg Q2W OLE"},{"description":"This arm consisted of participants who received CZP 400 mg Q4W in the Maintenance Period, who achieved a PASI50 response (had no relapse) at Week 48 and entered OLE on the CZP 200mg Q2W dose.","id":"FG019","title":"CZP 400 mg Q4W/CZP 200 mg Q2W OLE"},{"description":"This arm consisted of participants who received CZP 400 mg Q2W in the Maintenance Period, who achieved a PASI50 response (had no relapse) at Week 48 and entered OLE on the CZP 200mg Q2W dose.","id":"FG020","title":"CZP 400 mg Q2W/CZP 200 mg Q2W OLE"},{"description":"This arm consisted of participants who received open-label CZP 400mg Q2W in the Maintenance Period and entered OLE.","id":"FG021","title":"Esc CZP 400 mg Q2W/CZP 400 mg Q2W OLE"},{"description":"This arm consisted of participants from the Placebo-controlled Maintenance Period, who did not achieve PASI50 response (had relapse) and entered the 96-weeks OLE Period receiving CZP 400 mg Q2W.","id":"FG022","title":"Placebo/CZP 400 mg Q2W OLE"},{"description":"This arm consisted of participants who relapsed on CZP 200 mg Q2W, CZP 400 mg Q4W and 400 mg Q2W.","id":"FG023","title":"Any CZP/CZP 400 mg Q2W 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