{"groups":[{"description":"Ixazomib placebo-matching capsule, orally, once on Days 1, 8, and 15 of each 28-day cycle from Cycles 1 through 26.","id":"FG000","title":"Placebo"},{"description":"Ixazomib 3 mg, capsule, orally, once on Days 1, 8, and 15 of each 28-day cycle from Cycles 1 to 4 that may have been escalated to 4 mg thereafter up to Cycle 26.","id":"FG001","title":"Ixazomib"}],"periods":[{"dropWithdraws":[{"reasons":[{"groupId":"FG000","numSubjects":"8"},{"groupId":"FG001","numSubjects":"8"}],"type":"Lost to Follow-up"},{"reasons":[{"groupId":"FG000","numSubjects":"49"},{"groupId":"FG001","numSubjects":"76"}],"type":"Withdrawal by Patient"},{"reasons":[{"groupId":"FG000","numSubjects":"107"},{"groupId":"FG001","numSubjects":"159"}],"type":"Reason not Specified"},{"reasons":[{"groupId":"FG000","numSubjects":"2"},{"groupId":"FG001","numSubjects":"1"}],"type":"Missing"},{"reasons":[{"groupId":"FG000","numSubjects":"115"},{"groupId":"FG001","numSubjects":"181"}],"type":"Death"}],"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"281"},{"groupId":"FG001","numSubjects":"425"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"276"},{"groupId":"FG001","numSubjects":"426"}],"comment":"The safety population was defined as all participants who received at least 1 dose of ixazomib or placebo.\n\nThree placebo participants who erroneously received a single dose of ixazomib were included in the ixazomib arm of the safety population.","type":"Safety Population"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"281"},{"groupId":"FG001","numSubjects":"425"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}],"preAssignmentDetails":"Participants with newly diagnosed multiple myeloma not treated with stem cell transplantation (SCT) were enrolled and randomized in a 3:2 ratio to receive ixazomib or placebo respectively.","recruitmentDetails":"Participants took part in the study from 09 April 2015 to 26 August 2022."}