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13"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.99","value":"3.1"},{"groupId":"OG001","spread":"17.45","value":"-1.1"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"126"},{"groupId":"OG001","value":"204"}],"units":"Participants"}],"title":"Cycle 14"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.74","value":"2.2"},{"groupId":"OG001","spread":"17.65","value":"-0.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"115"},{"groupId":"OG001","value":"194"}],"units":"Participants"}],"title":"Cycle 15"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.57","value":"2.5"},{"groupId":"OG001","spread":"17.03","value":"0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"104"},{"groupId":"OG001","value":"184"}],"units":"Participants"}],"title":"Cycle 16"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.09","value":"2.4"},{"groupId":"OG001","spread":"18.09","value":"-0.2"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"100"},{"groupId":"OG001","value":"182"}],"units":"Participants"}],"title":"Cycle 17"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.40","value":"0.5"},{"groupId":"OG001","spread":"16.87","value":"1.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"91"},{"groupId":"OG001","value":"182"}],"units":"Participants"}],"title":"Cycle 18"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.07","value":"1.6"},{"groupId":"OG001","spread":"17.24","value":"1.1"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"82"},{"groupId":"OG001","value":"172"}],"units":"Participants"}],"title":"Cycle 19"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.95","value":"1.1"},{"groupId":"OG001","spread":"16.13","value":"0.4"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"74"},{"groupId":"OG001","value":"161"}],"units":"Participants"}],"title":"Cycle 20"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"16.39","value":"1.5"},{"groupId":"OG001","spread":"16.19","value":"1.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"72"},{"groupId":"OG001","value":"153"}],"units":"Participants"}],"title":"Cycle 21"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.55","value":"1.6"},{"groupId":"OG001","spread":"17.13","value":"1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"72"},{"groupId":"OG001","value":"147"}],"units":"Participants"}],"title":"Cycle 22"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"19.01","value":"2.1"},{"groupId":"OG001","spread":"16.96","value":"0.9"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"68"},{"groupId":"OG001","value":"137"}],"units":"Participants"}],"title":"Cycle 23"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"20.46","value":"-0.3"},{"groupId":"OG001","spread":"15.65","value":"2.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"64"},{"groupId":"OG001","value":"132"}],"units":"Participants"}],"title":"Cycle 24"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.80","value":"0.0"},{"groupId":"OG001","spread":"17.52","value":"0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"56"},{"groupId":"OG001","value":"125"}],"units":"Participants"}],"title":"Cycle 25"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"17.49","value":"2.8"},{"groupId":"OG001","spread":"17.26","value":"0.9"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"47"},{"groupId":"OG001","value":"106"}],"units":"Participants"}],"title":"Cycle 26"}],"denoms":[{"counts":[{"groupId":"OG000","value":"257"},{"groupId":"OG001","value":"391"}],"units":"Participants"}],"description":"The EORTC QLQ-C30 is a questionnaire to assess the overall quality of life of cancer patients. The change from baseline in GHS (EORTC QLQ-C30) score is presented. Participant responses to the question \"How would you rate your overall health during the past week?\" are scored on a 7-point scale (1=very poor to 7=excellent). Using linear transformation, raw scores are standardized, so that scores range from 0 to 100. A higher score indicates a better overall GHS.","dispersionType":"Standard Deviation","groups":[{"description":"Ixazomib 3 mg, capsule, orally, once on Days 1, 8, and 15 of each 28-day cycle from Cycles 1 through 26.","id":"OG000","title":"Placebo"},{"description":"Ixazomib 3 mg, capsule, orally, once on Days 1, 8, and 15 of each 28-day cycle from Cycles 1 to 4 that may have been escalated to 4 mg thereafter up to Cycle 26.","id":"OG001","title":"Ixazomib"}],"paramType":"MEAN","populationDescription":"ITT Population included all participants who were randomized and had post-randomization data. Overall number analyzed is the number of participants with data available for analyses. Number analyzed is the number of participants with data available for analyses for the specified time point.","reportingStatus":"POSTED","timeFrame":"Baseline, Cycles 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, and 26 (cycle length=28 days)","title":"Change From Baseline in the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) as Measured by the Global Health Status (GHS)","type":"SECONDARY","unitOfMeasure":"score on a scale"}