{"groups":[{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG000","title":"Dose Regimen A (DR-A) Escalation (0.16 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG001","title":"Dose Regimen A (DR-A) Escalation (0.32 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG002","title":"Dose Regimen A (DR-A) Escalation (0.64 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG003","title":"Dose Regimen A (DR-A) Escalation (1.25 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG004","title":"Dose Regimen A (DR-A) Escalation (2.10 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG005","title":"Dose Regiment A (DR-A) Escalation (3.10 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG006","title":"Dose Regimen A (DR-A) Escalation (4.40 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 4, 8 and 11 of a 21-day cycle\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG007","title":"Dose Regimen B (DR-B) Escalation (0.32 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG008","title":"Dose Regimen B (DR-B) Escalation (0.53 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG009","title":"Dose Regimen B (DR-B) Escalation (0.80 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG010","title":"Dose Regimen B (DR-B) Escalation (1.10 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG011","title":"Dose Regimen B (DR-B) Escalation (1.50 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG012","title":"Dose Regimen B (DR-B) Escalation (2.00 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG013","title":"Dose Regimen B (DR-B) Escalation (2.70 mg/kg)"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle.\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG014","title":"Dose Regimen A (DR-A) PTCL Expansion"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 3 and 5 of a 21-day cycle\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG015","title":"Dose Regimen C (DR-C) PTCL Expansion"},{"description":"Drug: ALRN-6924 Weight-based-dosing administered IV on days 1, 8 and 15 of a 28-day cycle Drug: Palbociclib Fixed-dose capsule administered orally on days 1 through 21 of a 28-day cycle\n\nALRN-6924: ALRN-6924 will be administered as an IV infusion","id":"FG016","title":"Combination With Palbociclib Expansion"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"5"},{"groupId":"FG001","numSubjects":"3"},{"groupId":"FG002","numSubjects":"4"},{"groupId":"FG003","numSubjects":"3"},{"groupId":"FG004","numSubjects":"6"},{"groupId":"FG005","numSubjects":"9"},{"groupId":"FG006","numSubjects":"11"},{"groupId":"FG007","numSubjects":"3"},{"groupId":"FG008","numSubjects":"5"},{"groupId":"FG009","numSubjects":"3"},{"groupId":"FG010","numSubjects":"4"},{"groupId":"FG011","numSubjects":"4"},{"groupId":"FG012","numSubjects":"5"},{"groupId":"FG013","numSubjects":"6"},{"groupId":"FG014","numSubjects":"21"},{"groupId":"FG015","numSubjects":"16"},{"groupId":"FG016","numSubjects":"34"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"},{"groupId":"FG001","numSubjects":"0"},{"groupId":"FG002","numSubjects":"0"},{"groupId":"FG003","numSubjects":"1"},{"groupId":"FG004","numSubjects":"1"},{"groupId":"FG005","numSubjects":"0"},{"groupId":"FG006","numSubjects":"1"},{"groupId":"FG007","numSubjects":"0"},{"groupId":"FG008","numSubjects":"0"},{"groupId":"FG009","numSubjects":"0"},{"groupId":"FG010","numSubjects":"0"},{"groupId":"FG011","numSubjects":"0"},{"groupId":"FG012","numSubjects":"0"},{"groupId":"FG013","numSubjects":"2"},{"groupId":"FG014","numSubjects":"1"},{"groupId":"FG015","numSubjects":"0"},{"groupId":"FG016","numSubjects":"7"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"5"},{"groupId":"FG001","numSubjects":"3"},{"groupId":"FG002","numSubjects":"4"},{"groupId":"FG003","numSubjects":"2"},{"groupId":"FG004","numSubjects":"5"},{"groupId":"FG005","numSubjects":"9"},{"groupId":"FG006","numSubjects":"10"},{"groupId":"FG007","numSubjects":"3"},{"groupId":"FG008","numSubjects":"5"},{"groupId":"FG009","numSubjects":"3"},{"groupId":"FG010","numSubjects":"4"},{"groupId":"FG011","numSubjects":"4"},{"groupId":"FG012","numSubjects":"5"},{"groupId":"FG013","numSubjects":"4"},{"groupId":"FG014","numSubjects":"20"},{"groupId":"FG015","numSubjects":"16"},{"groupId":"FG016","numSubjects":"27"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}]}