{"denomUnitsSelected":"Participants","description":"The quality-adjusted time without symptoms of disease progression or toxicity of treatment (Q-TWiST) score was used to measure overall health. Differences between treatment groups in the mean Q-TWiST score were calculated. For each score, a 95% confidence interval (CI) and two-sided P-value for testing the null hypothesis of no difference between treatment groups were conducted using a Z-test (with normal approximation), with standard errors calculated by the bootstrap method.","reportingStatus":"NOT_POSTED","timeFrame":"assessed at baseline and 2 years after initiation of treatment","title":"Overall Health","type":"SECONDARY"}