{"analyses":[{"groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.95","statisticalMethod":"t-test, 1 sided"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.3","value":"32.4"},{"groupId":"OG001","spread":"13.9","value":"32.0"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"},{"groupId":"OG001","value":"8"}],"units":"Participants"}],"description":"Average Area Under the Curve per assessment (aAUCpa) of QLQ H\\&N35 subscales including pain, swallowing, teeth, opening mouth, dry mouth, sticky saliva, senses problems, coughing, speech problems, felt ill, trouble with social contact, trouble with social eating, less sexuality, pain killers, nutritional supplements, feeding tube, weight loss, and weight gain. The QLQ H\\&N35 scoring algorithm was used for pain (questions 31-34) on 0-100 scales with higher scores representing worse symptoms. The aAUCpa for each subscale is calculated as the average of each AUC between each sequential assessment from treatment-initiation to the end of radiotherapy. For example; for each patient and subscale, the subscale values at treatment-initiation and assessment-1 are used to calculate an Area Under the Curve (AUC) for that assessment time-period. Then these AUCs for all available assessment time-periods up to the end of their radiotherapy are averaged to yield the aAUCpa per patient per subscale.","dispersionType":"Standard Deviation","groups":[{"description":"Patients receive a placebo oral rinse and gargle or swish for 60 seconds and then spit 5 times per day beginning within 3 days of the initiation of radiotherapy to 14 days following completion of radiotherapy.","id":"OG000","title":"Arm A (Placebo)"},{"description":"Patients receive acetylcysteine oral rinse and gargle or swish for 60 seconds then spit 5 times per day beginning within 3 days of the initiation of radiotherapy to 14 days following completion of radiotherapy.","id":"OG001","title":"Arm B (Rincinol)"}],"paramType":"MEAN","populationDescription":"Patients who completed the QLQ H\\&N Pain at all specified time points are included in this analysis.","reportingStatus":"POSTED","timeFrame":"Up to 90 days after completion of radiation therapy","title":"EORTC Quality of Life Questionnaire (QLQ) H&N Pain AUC","type":"SECONDARY","unitOfMeasure":"score on a scale"}