{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.5348","value":"-0.408"},{"groupId":"OG001","spread":"0.6521","value":"-0.540"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"75"},{"groupId":"OG001","value":"100"}],"units":"Participants"}],"description":"The HAQ-DI is a questionnaire specific for rheumatoid arthritis and consists of 20 questions referring to 8 domains: Dressing/grooming, arising, eating, walking, hygiene, reach, grip, and activities. Participants completed the questionnaire by answering the 20 questions on a scale of 0 (without difficulty) to 3 (unable to do). The total score ranges from 0 (no disability) to 3 (completely disabled). A negative change score indicates improvement. Data is reported for 2 groups.","dispersionType":"Standard Deviation","groups":[{"description":"Data for participants who received placebo in study WA17042 are included in this reporting group for data collected up until they received their first dose of rituximab in this study (study WA17531). Data from these participants collected after the first dose of rituximab are included in the rituximab reporting group.","id":"OG000","title":"Placebo"},{"description":"Participants received rituximab 1 g intravenously (IV) on Days 1 and 15 of each course of retreatment. In addition, participants received methotrexate 10-25 mg/week orally or parenterally, methylprednisolone 100 mg IV 30 minutes prior to both rituximab infusions, and a stable dose of folic acid ≥ 5 mg/week or equivalent, given as either a single dose or as divided daily doses.","id":"OG001","title":"Rituximab"}],"paramType":"MEAN","populationDescription":"Intent-to-treat population: All participants who received any part of an infusion of study medication in study WA17531. Only participants who had radiographs available at Baseline and Year 5 were included in the analysis.","reportingStatus":"POSTED","timeFrame":"Baseline to Year 5","title":"Change From Baseline in the Health Assessment Questionnaire-Disability Index (HAQ-DI) Score at Year 5","type":"SECONDARY","unitOfMeasure":"Units on a scale"}