{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.569","value":"-0.51"}]}],"title":"Retreatment 1 (n = 320)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.569","value":"-0.54"}]}],"title":"Retreatment 2 (n = 267)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.601","value":"-0.56"}]}],"title":"Retreatment 3 (n = 234)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.603","value":"-0.55"}]}],"title":"Retreatment 4 (n = 175)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.647","value":"-0.60"}]}],"title":"Retreatment 5 (n = 136)"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.653","value":"-0.55"}]}],"title":"Retreatment 6 (n = 92)"}],"denoms":[{"counts":[{"groupId":"OG000","value":"335"}],"units":"Participants"}],"description":"The HAQ-DI is a questionnaire specific for rheumatoid arthritis and consists of 20 questions referring to 8 domains: Dressing/grooming, arising, eating, walking, hygiene, reach, grip, and activities. Participants completed the questionnaire by answering the 20 questions on a scale of 0 (without difficulty) to 3 (unable to do). The total score ranges from 0 (no disability) to 3 (completely disabled). A negative change score indicates improvement.","dispersionType":"Standard Deviation","groups":[{"description":"Participants received rituximab 1 g intravenously (IV) on Days 1 and 15 of each course of retreatment. In addition, participants received methotrexate 10-25 mg/week orally or parenterally, methylprednisolone 100 mg IV 30 minutes prior to both rituximab infusions, and a stable dose of folic acid ≥ 5 mg/week or equivalent, given as either a single dose or as divided daily doses.","id":"OG000","title":"Rituximab"}],"paramType":"MEAN","populationDescription":"Intent-to-treat population: All participants who received any part of an infusion of study medication in study WA17531.","reportingStatus":"POSTED","timeFrame":"Baseline to the end of the retreatment period (up to 7 years, 6 months)","title":"Change From Baseline in the Health Assessment Questionnaire-Disability Index (HAQ-DI) Score","type":"SECONDARY","unitOfMeasure":"Units on a scale"}