{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"70.3","value":"807.6"},{"groupId":"OG001","spread":"68.7","value":"2137.9"},{"groupId":"OG002","spread":"50.8","value":"2421.2"},{"groupId":"OG003","spread":"29.9","value":"4433.1"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"6"},{"groupId":"OG001","value":"5"},{"groupId":"OG002","value":"14"},{"groupId":"OG003","value":"6"}],"units":"Participants"}],"description":"Pharmacokinetics of escalating dose levels of IMO 8400 administered by SC injection - Cmax.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"IMO-8400 0.6 mg/kg once weekly s.c.","id":"OG000","title":"IMO-8400 0.6 mg/kg 1x/wk"},{"description":"IMO-8400 1.2 mg/kg once weekly s.c.","id":"OG001","title":"IMO-8400 1.2 mg/kg 1x/wk"},{"description":"IMO-8400 1.2 mg/kg twice weekly s.c.","id":"OG002","title":"IMO-8400 1.2 mg/kg 2x/wk"},{"description":"IMO-8400 2.4 mg/kg once weekly s.c.","id":"OG003","title":"IMO-8400 2.4 mg/kg 1x/wk"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"PK Population","reportingStatus":"POSTED","timeFrame":"Cycle 1 Week 1 Day 1: Samples were obtained pre-dose (within 1 hr prior to injection) and post-dose at 1 hr (+/-5 min), 2 hrs (+/-10 min) and 4 hrs (+/-15 min)","title":"Pharmacokinetics of Escalating Dose Levels of IMO 8400 Administered by SC Injection - Cmax.","type":"SECONDARY","unitOfMeasure":"Cmax (ng/mL)"}