{"classes":[{"categories":[{"measurements":[{"comment":"NA indicates that the geometric mean and geometric coefficient of variation could not be calculated since the concentration was not quantifiable.","groupId":"OG000","spread":"NA","value":"NA"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"8"}],"units":"Participants"}],"title":"Day 1, Cycle 1,n=8"},{"categories":[{"measurements":[{"comment":"NA indicates that the geometric mean and geometric coefficient of variation could not be calculated since the concentration was not quantifiable.","groupId":"OG000","spread":"NA","value":"NA"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"}],"units":"Participants"}],"title":"Day 1, Cycle 2,n=4"},{"categories":[{"measurements":[{"comment":"NA indicates that the geometric mean and geometric coefficient of variation could not be calculated since the concentration was not quantifiable.","groupId":"OG000","spread":"NA","value":"NA"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"}],"units":"Participants"}],"title":"Day 1, Cycle 4,n=3"}],"denoms":[{"counts":[{"groupId":"OG000","value":"8"}],"units":"Participants"}],"description":"Blood samples were collected at designated timepoints. PK parameters of Cys-mcMMAF were calculated using non-compartmental methods. NA indicates that the geometric mean and geometric coefficient of variation could not be calculated since the concentration was not quantifiable.","dispersionType":"Geometric Coefficient of Variation","groups":[{"description":"Participants were administered a dose of 2.50 mg/kg GSK2857916 as IV infusion once every three weeks for a maximum of 16 cycles (1 cycle= 21 days).","id":"OG000","title":"Part 1: GSK2857916 2.50 mg/kg"}],"paramType":"GEOMETRIC_MEAN","populationDescription":"PK Part 1 Population. Only those participants with data available at the specified data points were analyzed (represented by n=X in the category titles).","reportingStatus":"POSTED","timeFrame":"Pre-dose and EOI of Day 1 (Cycle 1, Cycle 2 and Cycle 4)","title":"Ctrough of Cys-mcMMAF Following IV Dose of GSK2857916 in Participants With Relapsed/Refractory MM- Part 1: GSK2857916 2.50 mg/kg","type":"SECONDARY","unitOfMeasure":"Picograms per milliliter"}