{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Hb, Hb increased, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hb, Hb increased, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hb, Hb increased, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"18"}]}],"title":"Hb,Anemia, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"7"}]}],"title":"Hb, Anemia, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Hb, Anemia, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Lymph, Lymph count increased, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Lymph, Lymph count increased, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Lymph, Lymph count increased, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"18"}]}],"title":"Lymph, Lymph count decreased, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"Lymph, Lymph count decreased, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Lymph, Lymph count decreased, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"15"}]}],"title":"Neutro, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Neutro, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Neutro, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"32"}]}],"title":"PC, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"13"}]}],"title":"PC, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"PC, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Leuko, Leukocytosis, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Leuko, Leukocytosis, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"title":"Leuko, Leukocytosis, increase to Grade 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"16"}]}],"title":"Leuko, Leuko decreased, any grade increase"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Leuko, Leuko decreased, increase to Grade 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Leuko, Leuko decreased, increase to Grade 4"}],"denoms":[{"counts":[{"groupId":"OG000","value":"35"}],"units":"Participants"}],"description":"Blood samples were collected for the analysis of following hematology parameters: Hb, Lymph, Neutro, PC, and leuko. The laboratory parameters were graded according to NCI-CTCAE version 4.0. Grade 1: mild; Grade 2: moderate; Grade 3: severe or medically significant; Grade 4: life-threatening consequences; Grade 5: death related to AE. Baseline was defined as the latest pre-dose assessment with a non-missing value, including unscheduled visits.An increase is defined as an increase in CTCAE grade relative to Baseline grade. Data for worst-case post Baseline is presented.","groups":[{"description":"Participants with multiple myeloma were administered a dose of 3.40 mg/kg GSK2857916 as IV infusion once every three weeks for a maximum of 16 cycles (1 cycle=21 days).","id":"OG000","title":"Part 2: GSK2857916 3.40 mg/kg (MM)"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Part 2 MM Population","reportingStatus":"POSTED","timeFrame":"Baseline and Up to 24.2 months (maximum duration of follow-up from first dose to last contact or death)","title":"Number of Participants With Grade Change From Baseline in Hematology Data-Part 2 (MM)","type":"PRIMARY","unitOfMeasure":"Participants"}