{"denomUnitsSelected":"Participants","description":"Patients are classified as stage 0-IV according to the Rai system and categorized into one of the three risk groups:\n\nLow risk - Stage 0 Intermediate risk - Stage I or II High risk - Stage III or IV\n\nCR requires all of the following for at least 2 months:\n\n* Absence of lymphadenopathy by physical examination on 2 occasions at least 4 weeks apart and appropriate radiographic techniques. For patients whose only measurable disease at the time of enrollment is on CT scan, a CT scan is required and all lymph nodes must be ≤ 1.5 cm before classifying the patient a CR.\n* Absence of hepatomegaly or splenomegaly by physical examination\n* Absence of constitutional symptoms due to disease\n* Normal complete blood count\n* One marrow aspirate and biopsy should be performed 52 weeks after Day 1 of cycle 1 among patients with clinical and laboratory evidence of a CR to document a CR. The marrow sample must be at least normocellular with \\< 30% of nucleated cells being lymphocytes.","reportingStatus":"NOT_POSTED","timeFrame":"Assessed at baseline, every 3 months for the first 2 years, and every 6 months for years 3-5","title":"The Association Between Baseline Rai Stage and Complete Response (CR) Rate","type":"SECONDARY"}