{"groups":[{"description":"Escalating doses of total marrow irradiation (3Gy(gray), 6Gy, 9Gy, or 12Gy) with standard high dose melphalan prior to autologous stem cell rescue.\n\nTotal Marrow Irradiation (TMI): Subjects in this trial will receive total body irradiation (3Gy) per day for up to four days and as little as one day. Total IMT doses: 3Gy, 6Gy, 9Gy, or 12Gy.\n\nAutologous Transplant: Subjects will receive standard melphalan 200mg/m\\^2 (100mg/m\\^2 day-2 and day-1) conditioning with escalating doses of total marrow irradiation prior to autologous stem cell rescue.\n\nMelphalan: Subjects will receive standard melphalan 200mg/m\\^2 (100mg/m\\^2 day-2 and day-1) conditioning therapy prior to transplant.\n\nFilgrastim (G-CSF): Subjects to begin GCSF 5 μg/kg/d SC or IV on Day 5 and continue until ANC \\> 1000/mm\\^3 over period of 3 days.","id":"FG000","title":"Total Marrow Irradiation"}],"periods":[{"milestones":[{"achievements":[{"groupId":"FG000","numSubjects":"2"}],"type":"STARTED"},{"achievements":[{"groupId":"FG000","numSubjects":"2"}],"type":"COMPLETED"},{"achievements":[{"groupId":"FG000","numSubjects":"0"}],"type":"NOT COMPLETED"}],"title":"Overall Study"}],"recruitmentDetails":"1 ineligible"}