{"denoms":[{"counts":[{"groupId":"OG000","value":"0"}],"units":"Participants"}],"description":"Each of the tumor and mucosal markers will be dependent variables in repeated measures models that include serum and saliva markers as predictors. Graphical analyses will be used to characterize possible nonlinear relationships between variables. Linear or nonlinear regression, as appropriate, will be used to characterize the relationship between the putative predictors and outcomes. Subset analyses, considering, for example, differences in relationships between tumor markers and serum and saliva markers between smokers and non-smokers will be performed by means of indicator variables.","groups":[{"description":"Patients receive soy isoflavones PO for approximately 14 days before undergoing surgery.","id":"OG000","title":"Treatment (Soy Isoflavones)"}],"populationDescription":"We are seeking additional funding to hire the personnel to perform the serum/saliva markers. Until further notice markers will be unable to be analyzed.","reportingStatus":"POSTED","timeFrame":"Up to 12 months","title":"Correlations of Tumor p16 Methylation Status With Serum/Saliva Markers of p16, IL6, and VEGF","type":"PRIMARY"}