{"analyses":[{"ciLowerLimit":"0.25","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.76","estimateComment":"hazard ratio: blinatumomab + chemotherapy vs. chemotherapy alone","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.003","paramType":"Hazard Ratio (HR)","paramValue":"0.44","statisticalMethod":"Log Rank"}],"classes":[{"categories":[{"measurements":[{"comment":"Median OS not reached The 95% confidence intervals were not calculable because an insufficient number of participants reached the event at the final time point for assessment.","groupId":"OG000","lowerLimit":"NA","upperLimit":"NA","value":"NA"},{"comment":"Median OS not reached The upper limit of the 95% confidence interval was not calculable because an insufficient number of participants reached the event at the final time point for assessment.","groupId":"OG001","lowerLimit":"66.5","upperLimit":"NA","value":"NA"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"112"},{"groupId":"OG001","value":"112"}],"units":"Participants"}],"description":"Overall survival is defined as the time from randomization to death of any cause.","dispersionType":"95% Confidence Interval","groups":[{"description":"MRD negative patients received induction treatment and intensification treatment and then were randomized to receive blinatumomab plus chemotherapy.","id":"OG000","title":"MRD Negative - Blinatumomab + Chemotherapy"},{"description":"MRD negative patients received induction treatment and intensification treatment and then were randomized to receive chemotherapy.","id":"OG001","title":"MRD Negative - Chemotherapy"}],"paramType":"MEDIAN","populationDescription":"All MRD-negative patients randomized to either blinatumomab + chemotherapy or chemotherapy alone were included in this analysis.","reportingStatus":"POSTED","timeFrame":"Assessed every 3 months for 2 years, then every 6 months for 3 years, then annually for 5 years","title":"Overall Survival (OS) Among Patients Who Were MRD Negative After Induction and Intensification Chemotherapy","type":"PRIMARY","unitOfMeasure":"months"}