{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.41","value":"1.0"},{"groupId":"OG002","spread":"0.71","value":"-0.5"},{"groupId":"OG003","spread":"2.27","value":"-0.9"},{"groupId":"OG004","spread":"1.39","value":"0.8"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG009","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"1"}],"units":"Participants"}],"title":"Cycle 1 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"2.0"},{"groupId":"OG001","spread":"0.58","value":"-0.3"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG002","spread":"NA","value":"2.0"},{"groupId":"OG003","spread":"1.41","value":"0.3"},{"groupId":"OG004","spread":"1.79","value":"0.0"},{"groupId":"OG005","spread":"8.08","value":"4.7"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"groupId":"OG007","spread":"0.00","value":"0.0"},{"groupId":"OG008","spread":"0.00","value":"0.0"},{"groupId":"OG009","spread":"1.15","value":"-0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"1"},{"groupId":"OG003","value":"9"},{"groupId":"OG004","value":"16"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"2"},{"groupId":"OG008","value":"2"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 2 Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.00","value":"2.0"},{"groupId":"OG001","spread":"0.58","value":"0.3"},{"groupId":"OG002","spread":"0.71","value":"-0.5"},{"groupId":"OG003","spread":"1.85","value":"-0.6"},{"groupId":"OG004","spread":"1.52","value":"0.2"},{"groupId":"OG005","spread":"8.49","value":"5.0"},{"groupId":"OG006","spread":"2.83","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.00","value":"-1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"8"},{"groupId":"OG004","value":"15"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 3 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"5.0"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG002","spread":"2.12","value":"1.5"},{"groupId":"OG003","spread":"1.81","value":"-1.1"},{"groupId":"OG004","spread":"1.47","value":"0.0"},{"groupId":"OG005","spread":"6.24","value":"2.0"},{"groupId":"OG006","spread":"3.54","value":"-0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.15","value":"-0.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"8"},{"groupId":"OG004","value":"14"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 4 Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"3.54","value":"0.5"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG002","spread":"2.12","value":"1.5"},{"groupId":"OG003","spread":"1.25","value":"0.3"},{"groupId":"OG004","spread":"1.72","value":"-0.2"},{"groupId":"OG005","spread":"8.14","value":"4.7"},{"groupId":"OG006","spread":"6.36","value":"0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"11"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 5 Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.12","value":"2.5"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG002","spread":"1.41","value":"1.0"},{"groupId":"OG003","spread":"2.70","value":"-0.4"},{"groupId":"OG004","spread":"0.90","value":"0.3"},{"groupId":"OG005","spread":"5.86","value":"4.3"},{"groupId":"OG006","spread":"4.24","value":"2.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"2.31","value":"-1.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"11"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 6 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"2.0"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG002","spread":"2.12","value":"1.5"},{"groupId":"OG003","spread":"1.21","value":"-0.1"},{"groupId":"OG004","spread":"0.90","value":"0.4"},{"groupId":"OG005","spread":"8.33","value":"4.7"},{"groupId":"OG006","spread":"4.24","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.15","value":"-0.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"12"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 7 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"-4.0"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG002","spread":"2.12","value":"1.5"},{"groupId":"OG003","spread":"2.34","value":"-0.1"},{"groupId":"OG004","spread":"1.34","value":"0.2"},{"groupId":"OG005","spread":"7.81","value":"3.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"2"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"12"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 8 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG002","spread":"NA","value":"0.0"},{"groupId":"OG003","spread":"2.31","value":"-1.0"},{"groupId":"OG004","spread":"2.10","value":"0.3"},{"groupId":"OG005","spread":"8.49","value":"6.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG006","spread":"NA","value":"6.0"},{"groupId":"OG009","spread":"0.58","value":"-0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"1"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"11"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"1"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 9 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"-5.0"},{"groupId":"OG001","spread":"0.71","value":"0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG002","spread":"NA","value":"0.0"},{"groupId":"OG003","spread":"0.00","value":"0.0"},{"groupId":"OG004","spread":"0.88","value":"-0.1"},{"groupId":"OG005","spread":"9.19","value":"6.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG006","spread":"NA","value":"6.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.53","value":"-1.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"1"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"10"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"1"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 10 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG002","spread":"NA","value":"0.0"},{"groupId":"OG003","spread":"1.70","value":"0.3"},{"groupId":"OG004","spread":"1.53","value":"-0.2"},{"groupId":"OG005","spread":"8.49","value":"7.0"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"1"},{"groupId":"OG003","value":"7"},{"groupId":"OG004","value":"12"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 11 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"2.19","value":"-0.6"},{"groupId":"OG004","spread":"2.33","value":"-0.2"},{"groupId":"OG005","spread":"9.19","value":"6.5"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.58","value":"-0.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"12"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 12 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"2.22","value":"0.5"},{"groupId":"OG005","spread":"7.78","value":"5.5"},{"groupId":"OG006","spread":"4.24","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"10"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 13 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"3.20","value":"-0.3"},{"groupId":"OG004","spread":"0.79","value":"0.3"},{"groupId":"OG005","spread":"8.49","value":"6.0"},{"groupId":"OG006","spread":"3.54","value":"2.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"6"},{"groupId":"OG004","value":"11"},{"groupId":"OG005","value":"2"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 14 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"5.43","value":"-1.7"},{"groupId":"OG004","spread":"1.36","value":"0.1"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.58","value":"-0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"6"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 15 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"1.41","value":"0.0"},{"groupId":"OG003","spread":"2.49","value":"-0.2"},{"groupId":"OG004","spread":"1.99","value":"-0.2"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"1.0"},{"groupId":"OG006","spread":"6.36","value":"1.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 16 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"2.83","value":"-2.0"},{"groupId":"OG003","spread":"1.95","value":"0.6"},{"groupId":"OG004","spread":"1.17","value":"0.1"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-3.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.53","value":"-1.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 17 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"1.73","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-2.0"},{"groupId":"OG006","spread":"4.24","value":"3.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 18 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"2.65","value":"-0.6"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"4.95","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 19 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"1.41","value":"0.0"},{"groupId":"OG004","spread":"2.12","value":"0.7"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 20 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"groupId":"OG003","spread":"1.41","value":"0.0"},{"groupId":"OG004","spread":"2.09","value":"0.1"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 21 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"1.52","value":"0.4"},{"groupId":"OG004","spread":"1.45","value":"0.1"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"-1.0"},{"groupId":"OG009","spread":"0.58","value":"-0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"9"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 22 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"1.41","value":"0.0"},{"groupId":"OG004","spread":"1.81","value":"0.1"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-1.0"},{"groupId":"OG006","spread":"3.54","value":"1.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"4.04","value":"-2.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"8"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 23 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"0.89","value":"-0.4"},{"groupId":"OG004","spread":"0.74","value":"0.6"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"1.0"},{"groupId":"OG006","spread":"4.95","value":"1.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"8"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 24 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"2.27","value":"-0.9"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-2.0"},{"groupId":"OG006","spread":"4.95","value":"2.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"7"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 25 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"2.77","value":"-0.4"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-1.0"},{"groupId":"OG006","spread":"4.24","value":"2.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.58","value":"-0.3"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"8"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 26 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"1.79","value":"0.8"},{"groupId":"OG004","spread":"2.67","value":"-0.1"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-1.0"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.41","value":"-1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"5"},{"groupId":"OG004","value":"7"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 27 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"2.00","value":"1.0"},{"groupId":"OG004","spread":"0.76","value":"0.7"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"-2.0"},{"groupId":"OG006","spread":"2.83","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"4"},{"groupId":"OG004","value":"7"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 28 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"2.12","value":"-1.5"},{"groupId":"OG003","spread":"1.73","value":"0.5"},{"groupId":"OG004","spread":"1.81","value":"0.1"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"4"},{"groupId":"OG004","value":"8"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 29 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"1.50","value":"0.8"},{"groupId":"OG004","spread":"0.55","value":"0.4"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"2.83","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"1.00","value":"-1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"4"},{"groupId":"OG004","value":"5"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 30 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"groupId":"OG003","spread":"2.65","value":"1.0"},{"groupId":"OG004","spread":"0.82","value":"0.7"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG005","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"4.24","value":"3.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"3"},{"groupId":"OG004","value":"6"},{"groupId":"OG005","value":"1"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"3"}],"units":"Participants"}],"title":"Cycle 31 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"2.31","value":"1.3"},{"groupId":"OG004","spread":"0.55","value":"0.4"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"3"},{"groupId":"OG004","value":"5"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 32 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"2.31","value":"1.3"},{"groupId":"OG004","spread":"0.58","value":"0.5"},{"groupId":"OG006","spread":"3.54","value":"3.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"3"},{"groupId":"OG004","value":"4"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 33 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"groupId":"OG003","spread":"0.00","value":"0.0"},{"groupId":"OG004","spread":"0.50","value":"0.3"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"groupId":"OG009","spread":"0.00","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"2"},{"groupId":"OG004","value":"4"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"2"}],"units":"Participants"}],"title":"Cycle 34 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"groupId":"OG004","spread":"0.50","value":"0.3"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG009","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"4"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"1"}],"units":"Participants"}],"title":"Cycle 35 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"groupId":"OG004","spread":"0.00","value":"0.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG009","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"3"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"1"}],"units":"Participants"}],"title":"Cycle 36 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"-1.0"},{"groupId":"OG004","spread":"0.00","value":"0.0"},{"groupId":"OG006","spread":"4.95","value":"3.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 37 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"groupId":"OG004","spread":"0.00","value":"0.0"},{"groupId":"OG006","spread":"2.83","value":"3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 38 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"groupId":"OG004","spread":"0.71","value":"-0.5"},{"groupId":"OG006","spread":"4.95","value":"3.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"2"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 39 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"-1.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG004","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"1"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 40 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG004","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"6.36","value":"1.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"1"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 41 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG004","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"1"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 42 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.00","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"groupId":"OG006","spread":"4.24","value":"4.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 43 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"1.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"-1.0"},{"groupId":"OG006","spread":"4.24","value":"3.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 44 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"1.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG006","spread":"NA","value":"1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"1"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 45 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"-1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 46 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"0.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 47 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"-3.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 48 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 49 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"-3.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 50 Day 1"},{"categories":[{"measurements":[{"groupId":"OG001","spread":"0.71","value":"-0.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"2"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 51 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG001","spread":"NA","value":"1.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"1"},{"groupId":"OG002","value":"0"},{"groupId":"OG003","value":"0"},{"groupId":"OG004","value":"0"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"0"},{"groupId":"OG009","value":"0"}],"units":"Participants"}],"title":"Cycle 52 Day 1"},{"categories":[{"measurements":[{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG000","spread":"NA","value":"-8.0"},{"groupId":"OG002","spread":"1.15","value":"0.7"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG003","spread":"NA","value":"-2.0"},{"groupId":"OG004","spread":"5.19","value":"-2.3"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG008","spread":"NA","value":"-15.0"},{"comment":"Standard deviation could not be calculated as only 1 participant was analyzed.","groupId":"OG009","spread":"NA","value":"0.0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"1"},{"groupId":"OG001","value":"0"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"1"},{"groupId":"OG004","value":"4"},{"groupId":"OG005","value":"0"},{"groupId":"OG006","value":"0"},{"groupId":"OG007","value":"0"},{"groupId":"OG008","value":"1"},{"groupId":"OG009","value":"1"}],"units":"Participants"}],"title":"End of treatment"}],"denoms":[{"counts":[{"groupId":"OG000","value":"2"},{"groupId":"OG001","value":"3"},{"groupId":"OG002","value":"3"},{"groupId":"OG003","value":"9"},{"groupId":"OG004","value":"16"},{"groupId":"OG005","value":"3"},{"groupId":"OG006","value":"2"},{"groupId":"OG007","value":"2"},{"groupId":"OG008","value":"3"},{"groupId":"OG009","value":"4"}],"units":"Participants"}],"description":"In Phase 1, the MMSE was collected to assess mental status. The MMSE is a 30 item questionnaire that tests 5 areas of cognitive function: orientation, registration, attention and calculation, recall and language. The maximum score is 30 and minimum score is 0. Highest score indicates no cognitive impairment, lowest score indicates severe cognitive impairment. The MMSE was removed under Amendment 6 of the study protocol, and not required for Phase 2, as the tool was not considered meaningful for assessment of cognitive function.","dispersionType":"Standard Deviation","groups":[{"description":"PF-06463922 10 mg was orally given once daily (QD) on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG000","title":"10 mg QD (Phase 1)"},{"description":"PF-06463922 25 mg was orally given QD in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal. Midazolam 2 mg was orally given QD on Day -7 and Cycle 1 Day 15.","id":"OG001","title":"25 mg QD (Phase 1)"},{"description":"PF-06463922 50 mg was orally given QD on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG002","title":"50 mg QD (Phase 1)"},{"description":"PF-06463922 75 mg was orally given QD on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG003","title":"75 mg QD (Phase 1)"},{"description":"PF-06463922 100 mg was orally given QD on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG004","title":"100 mg QD (Phase 1)"},{"description":"PF-06463922 150 mg was orally given QD in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal. Midazolam 2 mg was orally given QD on Day -7 and Cycle 1 Day 15.","id":"OG005","title":"150 mg QD (Phase 1)"},{"description":"PF-06463922 200 mg was orally given QD on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG006","title":"200 mg QD (Phase 1)"},{"description":"PF-06463922 35 mg was orally given twice daily (BID) on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG007","title":"35 mg BID (Phase 1)"},{"description":"PF-06463922 75 mg was orally given BID on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG008","title":"75 mg BID (Phase 1)"},{"description":"PF-06463922 100 mg was orally given BID on Day -7 and in 21-day cycles from Cycle 1 Day 1 until progression of disease (unless clinical benefit was still achievable), unacceptable toxicity, death or consent withdrawal.","id":"OG009","title":"100 mg BID (Phase 1)"}],"paramType":"MEAN","populationDescription":"MMSE assessment evaluable analysis set included all participants in the safety analysis set (all participants who received at least 1 dose of PF-06463922) who completed a baseline and at least 1 post-baseline assessment. Here, \"Overall Number of Participants Analyzed\" signifies participants evaluable for this outcome measure. Here, \"Number Analyzed\" signifies participants evaluable for specified rows.","reportingStatus":"POSTED","timeFrame":"Baseline, Day 1 of Cycle 1-52, and end of treatment (up to 3 years)","title":"Change From Baseline in Mini Mental State Examination (MMSE) Score (Phase 1)","type":"SECONDARY","unitOfMeasure":"Units on a scale"}