{"denomUnitsSelected":"Participants","description":"Scale score trajectories over time will be examined using stream plots and mean plots with standard deviation error bars overall. Changes from baseline at each cycle will be statistically tested using paired t-tests, and standardized response means (mean of the change from baseline scores at a given cycle, divided by the standard deviation of the change scores) will be interpreted (after applying Middel's adjustment) using Cohen's cut-offs. Correlation between outcomes will employ Pearson and/or Spearman correlations at individual time points.","reportingStatus":"NOT_POSTED","timeFrame":"Baseline up to 1 year","title":"Change in Patient-reported Outcomes (Quality of Life and Symptoms)","type":"OTHER_PRE_SPECIFIED"}