{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"26.9","value":"61.8"},{"groupId":"OG001","spread":"20.8","value":"65.3"},{"groupId":"OG002","spread":"22.3","value":"66.8"},{"groupId":"OG003","spread":"24.1","value":"65.6"},{"groupId":"OG004","spread":"25.6","value":"74.5"},{"groupId":"OG005","spread":"29.0","value":"76.6"},{"groupId":"OG006","spread":"26.4","value":"75"},{"groupId":"OG007","spread":"29.1","value":"84.7"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"62"},{"groupId":"OG001","value":"60"},{"groupId":"OG002","value":"57"},{"groupId":"OG003","value":"55"},{"groupId":"OG004","value":"46"},{"groupId":"OG005","value":"41"},{"groupId":"OG006","value":"30"},{"groupId":"OG007","value":"10"}],"units":"Participants"}],"title":"Physical Functioning"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"23.1","value":"61.9"},{"groupId":"OG001","spread":"25.2","value":"69.3"},{"groupId":"OG002","spread":"22.5","value":"72"},{"groupId":"OG003","spread":"21.4","value":"73.7"},{"groupId":"OG004","spread":"21","value":"78.6"},{"groupId":"OG005","spread":"20.3","value":"84.2"},{"groupId":"OG006","spread":"23.3","value":"79"},{"groupId":"OG007","spread":"19.2","value":"85.5"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"62"},{"groupId":"OG001","value":"59"},{"groupId":"OG002","value":"57"},{"groupId":"OG003","value":"55"},{"groupId":"OG004","value":"46"},{"groupId":"OG005","value":"41"},{"groupId":"OG006","value":"30"},{"groupId":"OG007","value":"10"}],"units":"Participants"}],"title":"Emotional Functioning"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"18.8","value":"80.3"},{"groupId":"OG001","spread":"21.6","value":"79.2"},{"groupId":"OG002","spread":"18.4","value":"79.6"},{"groupId":"OG003","spread":"19.8","value":"79.2"},{"groupId":"OG004","spread":"20.1","value":"84.5"},{"groupId":"OG005","spread":"17.9","value":"87.8"},{"groupId":"OG006","spread":"22.8","value":"82.5"},{"groupId":"OG007","spread":"13.5","value":"92.6"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"62"},{"groupId":"OG001","value":"59"},{"groupId":"OG002","value":"56"},{"groupId":"OG003","value":"55"},{"groupId":"OG004","value":"46"},{"groupId":"OG005","value":"41"},{"groupId":"OG006","value":"30"},{"groupId":"OG007","value":"10"}],"units":"Participants"}],"title":"Social Functioning"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"25.4","value":"63.2"},{"groupId":"OG001","spread":"25.6","value":"68.5"},{"groupId":"OG002","spread":"25.3","value":"67.1"},{"groupId":"OG003","spread":"25.2","value":"70.5"},{"groupId":"OG004","spread":"21.7","value":"80.3"},{"groupId":"OG005","spread":"22.9","value":"82.2"},{"groupId":"OG006","spread":"22.5","value":"78.2"},{"groupId":"OG007","spread":"19.4","value":"81"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"61"},{"groupId":"OG001","value":"56"},{"groupId":"OG002","value":"52"},{"groupId":"OG003","value":"53"},{"groupId":"OG004","value":"41"},{"groupId":"OG005","value":"41"},{"groupId":"OG006","value":"29"},{"groupId":"OG007","value":"10"}],"units":"Participants"}],"title":"School Functioning"}],"denoms":[{"counts":[{"groupId":"OG000","value":"62"},{"groupId":"OG001","value":"60"},{"groupId":"OG002","value":"57"},{"groupId":"OG003","value":"55"},{"groupId":"OG004","value":"46"},{"groupId":"OG005","value":"41"},{"groupId":"OG006","value":"30"},{"groupId":"OG007","value":"10"}],"units":"Participants"}],"description":"Parent's assessment of child's physical, emotional, social and school functioning over multiple time points.\n\nThe QL scoring is a 5-point Likert scale from 0 (never) to 4 (almost always). Scores are transformed on a scale from 0 to 100. Items are reverse scored and linearly transformed to a 0-100 scale as follows: 0=100, 1=75, 2=50, 3=25, and 4=0. Total score is the sum of all items over the number of items answered on all scales. For both the total score and subscales the range is 0-100. The total score is the sum of all items from each subscale, over the number of items answered on the scale. The total score is the sum of all items on the scale over the number of items answer. If \\>50% of the items are missing the score should not be computed. If \\>50% are completed, impute the mean of the completed items in a scale. The Higher the score the better quality of life.","dispersionType":"Standard Deviation","groups":[{"description":"At Diagnosis (baseline)","id":"OG000","title":"Timepoint 1 (T1)"},{"description":"Course 2 Day 1","id":"OG001","title":"Timepoint 4 (T4)"},{"description":"Course 3 Day 1","id":"OG002","title":"Timepoint 6 (T6)"},{"description":"Course 6 Day 1","id":"OG003","title":"Timepoint 8 (T8)"},{"description":"4-6 weeks after chemotherapy or 4-6 weeks after radiation","id":"OG004","title":"Timepoint 10 (T10)"},{"description":"1 year off therapy","id":"OG005","title":"Timepoint 11 (T11)"},{"description":"2 years off therapy (approximately 2 years and 8 months","id":"OG006","title":"Timepoint 12 (T12)"},{"description":"5 years off therapy (approximately 5 years and 8 months)","id":"OG007","title":"Timepoint 13 (T13)"}],"paramType":"MEAN","populationDescription":"Each institution made the decision whether to complete the QoL objective. Participation in the Quality of Life part of the trial is voluntary for participating institutions and voluntary by parent.","reportingStatus":"POSTED","timeFrame":"At various time points from diagnosis through 5 years off therapy. (up to approximately 6 years from enrollment)","title":"Parent Proxy Quality of Life (QoL)","type":"SECONDARY","unitOfMeasure":"score on a scale"}