{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"1145.164","value":"2020.76"},{"groupId":"OG001","spread":"1587.586","value":"2276.37"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"196"},{"groupId":"OG001","value":"267"}],"units":"Participants"}],"title":"Cycle 1 Day 15"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"935.503","value":"1652.27"},{"groupId":"OG001","spread":"1039.953","value":"1689.83"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"186"},{"groupId":"OG001","value":"242"}],"units":"Participants"}],"title":"Cycle 2 Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"952.903","value":"1557.32"},{"groupId":"OG001","spread":"1054.346","value":"1552.09"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"159"},{"groupId":"OG001","value":"174"}],"units":"Participants"}],"title":"Cycle 3 Day 1"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"765.940","value":"1530.41"},{"groupId":"OG001","spread":"1026.999","value":"1629.14"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"142"},{"groupId":"OG001","value":"149"}],"units":"Participants"}],"title":"Cycle 4 Day 1"}],"denoms":[{"counts":[{"groupId":"OG000","value":"196"},{"groupId":"OG001","value":"267"}],"units":"Participants"}],"description":"Per protocol, the secondary PK endpoint, trough (Cmin) concentrations of rucaparib were summarized with descriptive statistics overall and by cycle in all patients with at least one PK sample collected. Blood samples for trough level PK analysis of rucaparib were drawn at the following timepoints only: on Day 15 of Cycle 1 and on Day 1 of Cycles 2, 3, and 4. Data for other timepoints is not available.","dispersionType":"Standard Deviation","groups":[{"description":"Includes all Part 1 patients","id":"OG000","title":"Part 1 Overall"},{"description":"Includes all Part 2 patients","id":"OG001","title":"Part 2 Overall"}],"paramType":"MEAN","populationDescription":"All Part 1 and Part 2 patients with at least one PK sample collected","reportingStatus":"POSTED","timeFrame":"Cycle 1 Day 15 to Cycle 4 Day 1, or approximately 10 weeks","title":"Steady State Trough (Cmin) Level Rucaparib Concentrations","type":"SECONDARY","unitOfMeasure":"ng/mL"}