{"analyses":[{"ciLowerLimit":"0.332","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"0.736","estimateComment":"Lapatinib Plus Capecitabine is the reference.","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY","pValue":"0.0004","paramType":"Hazard Ratio (HR)","paramValue":"0.495","statisticalMethod":"Log Rank"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"5.62","upperLimit":"11.17","value":"8.54"},{"groupId":"OG001","lowerLimit":"4.21","upperLimit":"6.41","value":"5.55"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"84"},{"groupId":"OG001","value":"72"}],"units":"Participants"}],"description":"The Duration of Response (DOR) is for Central Assessment for the Population that Had a Response with Measurable Disease at Screening.\n\nDuration of response is measured from the time at which measurement criteria are first met for CR or PR (whichever status is recorded first) until the first date of recurrence or progressive disease (PD) or death is objectively documented, taking as a reference for PD the smallest measurements recorded since enrollment, per RECIST v1.1. This value is censored at the last valid tumor assessment if PD or death has not been documented.","dispersionType":"95% Confidence Interval","groups":[{"description":"neratinib 240 mg orally, once daily with food, continuously in 21 day cycles, and capecitabine 1500 mg/m\\^2 daily in 2 evenly divided doses, orally with water within 30 minutes after a meal, taken on days 1 to 14 of each 21 day cycle.","id":"OG000","title":"Neratinib Plus Capecitabine"},{"description":"lapatinib 1250 mg orally, once daily, continuously in 21 day cycles, and capecitabine 2000 mg/m\\^2 daily in 2 evenly divided doses, orally with water within 30 minutes after a meal, taken on days 1 to 14 of each 21 day cycle.","id":"OG001","title":"Lapatinib Plus Capecitabine"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"From start date of response after randomization to first PD, up to 33 months.The result is based on primary analysis data cut.","title":"Duration of Response (DOR) - Central Assessment (Population That Had a Response With Measurable Disease at Screening)","type":"SECONDARY","unitOfMeasure":"months"}