{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.01","value":"0.01"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"10"}],"units":"Participants"}],"description":"Lambda(z) is defined as terminal rate-constant which reflect the speed of drug elimination in vivo (within the living), and is estimated by log-linear regression analysis of the terminal phase of the plasma concentration versus time curve for at least 3 points.","dispersionType":"Standard Deviation","groups":[{"description":"Participants received 1.3 mg per m\\^2 of bortezomib on Days 1, 4, 8, and 11 of each 3-week cycle for up to 8 cycles.","id":"OG000","title":"Bortezomib"}],"paramType":"MEAN","populationDescription":"The PP population included all the participants who received study medications as per the administration schedule and for whom blood samples were collected at all scheduled time points.","reportingStatus":"POSTED","timeFrame":"0 hour (Pre-dose) and 0.08, 0.25, 0.5, 1, 2, 4, 6, 8, 12, 24, 48, 72 hours (post-dose) on Day 11 of Cycle 1","title":"Terminal Rate Constant (Lambda[z]) of Bortezomib on Day 11 of Cycle 1","type":"PRIMARY","unitOfMeasure":"Per Hour"}