{"analyses":[{"ciLowerLimit":"0.777","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"1.177","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER_LEGACY","pValue":"0.337750","pValueComment":"1-sided p-value from the stratified log-rank test.","paramType":"Hazard Ratio (HR)","paramValue":"0.956","statisticalMethod":"Stratified Log Rank"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"49.8","upperLimit":"60.8","value":"53.9"},{"groupId":"OG001","lowerLimit":"43.7","upperLimit":"58.9","value":"51.2"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"444"},{"groupId":"OG001","value":"222"}],"units":"Participants"}],"description":"OS was defined as the time from date of randomization to date of death due to any cause. Participants without survival data beyond the date of their last follow-up were censored on the last date they were known to be alive. Data for this outcome measure was reported at primary analysis.","dispersionType":"95% Confidence Interval","groups":[{"description":"Participants received letrozole 2.5 milligram (mg) orally QD (once daily) combined with palbociclib 125 mg QD for 21 days of every-28-day cycle, followed by 7 days off treatment.","id":"OG000","title":"Palbociclib Plus Letrozole"},{"description":"Participants received letrozole 2.5 mg orally QD combined with placebo QD for 21 days of every-28-day cycle, followed by 7 days off treatment.","id":"OG001","title":"Placebo Plus Letrozole"}],"paramType":"MEDIAN","populationDescription":"ITT population or full analysis set included all participants who were randomized, with study medication, regardless of whether participants received study medication or received a different drug from that to which they were randomized.","reportingStatus":"POSTED","timeFrame":"From date of randomization until death due to any cause or censored, (assessed up to data cut-off date of 15-Nov-2021, approximately 8.7 years)","title":"Overall Survival (OS): Primary Analysis","type":"SECONDARY","unitOfMeasure":"Months"}