{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Blood bilirubin increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Chills"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Constipation"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Cough"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Creatinine increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Dehydration"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Dizziness"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Dyspepsia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Dyspnea"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Blepharitis"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Fatigue"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Flushing"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Gastroesophageal reflux disease"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Feverish"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Generalized muscle weakness"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Headache"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Hiccups"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Hyperkalemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Hypertension"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Hypocalcemia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"hyponatremia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"7"}]}],"title":"Infusion related reaction"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Insomnia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Lung infection"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Lymph node pain"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Lymphocyte count increased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Nausea"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Neutrophil count decreased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Palpitations"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Paresthesia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"peripheral sensory neuropathy"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Platelet count decreased"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Rash acneiform"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Rash maculo-papular"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Aspergillus Pneumonia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Sinus tachycardia"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Sinusitis"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Rash"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Lesions on face, neck, scalp"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Guttate Psoriasis (Exacerbation of Symptoms)"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Skin infection, Eyelid"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Upper respiratory infection"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Wheezing"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"White blood cell decreased"}],"denoms":[{"counts":[{"groupId":"OG000","value":"12"}],"units":"Participants"}],"description":"Toxicities will be graded according to the NCI CTCAE v4.0.","groups":[{"description":"Ofatumumab will be infused intravenously on day 1 (300 mg initial dose), followed one week later by 2000 mg weekly for 7 doses, followed 4 weeks later by 2000 mg every 4 weeks for 4 doses. Two units (approximately 200 or 250 ml) of FFP will be administered prior to ofatumumab(with the exception of the first dose). A unit of fresh frozen plasma is approximately 250ml (or half a pint).\n\nOfatumumab + Fresh Frozen Plasma","id":"OG000","title":"Ofatumumab + Fresh Frozen Plasma"}],"paramType":"COUNT_OF_PARTICIPANTS","reportingStatus":"POSTED","timeFrame":"Up to two years","title":"Number of Participants With Toxicities","type":"SECONDARY","unitOfMeasure":"Participants"}