{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"160"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"30"}],"units":"Participants"}],"description":"Maximum Tolerated Dose (MTD) was defined as the dose in which less than 2 of up to 6 patients developed a Dose Limiting Toxicity (DLT).","groups":[{"description":"Patients receiving oral administration of afatinib film-coated tablet once daily for three days, repeated every 14 days, during each 28-day cycle.","id":"OG000","title":"Afatinib"}],"paramType":"NUMBER","populationDescription":"Treated set including patients eligible for MTD determination","reportingStatus":"POSTED","timeFrame":"28 days","title":"Maximum Tolerated Dose","type":"PRIMARY","unitOfMeasure":"mg"}