{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.583","upperLimit":"4.283","value":"1.5500"},{"groupId":"OG001","lowerLimit":"0.550","upperLimit":"2.100","value":"0.9667"},{"groupId":"OG002","lowerLimit":"0.517","upperLimit":"1.033","value":"0.5500"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"10"},{"groupId":"OG002","value":"5"}],"units":"Participants"}],"title":"Week1 AM dose;n=4,10,5"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.917","upperLimit":"4.000","value":"1.9583"},{"groupId":"OG001","lowerLimit":"0.967","upperLimit":"4.167","value":"1.9667"},{"groupId":"OG002","lowerLimit":"1.017","upperLimit":"7.733","value":"1.9833"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"9"},{"groupId":"OG002","value":"5"}],"units":"Participants"}],"title":"Week1 PM dose;n=4,9,5"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.167","upperLimit":"2.067","value":"1.1833"},{"groupId":"OG001","lowerLimit":"0.250","upperLimit":"2.017","value":"1.0667"},{"groupId":"OG002","lowerLimit":"0.183","upperLimit":"1.000","value":"0.5833"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"7"},{"groupId":"OG002","value":"3"}],"units":"Participants"}],"title":"Week3 AM dose;n=3,7,3"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"0.500","upperLimit":"2.083","value":"1.0000"},{"groupId":"OG001","lowerLimit":"0.000","upperLimit":"2.083","value":"1.4500"},{"groupId":"OG002","lowerLimit":"1.900","upperLimit":"2.067","value":"2.0667"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"3"},{"groupId":"OG001","value":"6"},{"groupId":"OG002","value":"3"}],"units":"Participants"}],"title":"Week3 PM dose;n=3,6,3"}],"denoms":[{"counts":[{"groupId":"OG000","value":"4"},{"groupId":"OG001","value":"10"},{"groupId":"OG002","value":"5"}],"units":"Participants"}],"description":"Blood samples were collected at indicated time points post ante-meridiem (AM) and post-meridiem (PM) dose for pharmacokinetic analysis of GSK525762.","dispersionType":"Full Range","groups":[{"description":"Participants were administered twice daily (BID) oral dose of 20 mg GSK525762.","id":"OG000","title":"Part 1: GSK525762 20 mg BID"},{"description":"Participants were administered twice daily oral dose of 30 mg GSK525762.","id":"OG001","title":"Part 1: GSK525762 30 mg BID"},{"description":"Participants were administered twice daily oral dose of 40 mg GSK525762.","id":"OG002","title":"Part 1: GSK525762 40 mg BID"}],"paramType":"MEDIAN","populationDescription":"PK Parameter Population. Only those participants with data available at the specified time points were analyzed (indicated by n=X in category titles)","reportingStatus":"POSTED","timeFrame":"pre-dose,0.25,0.5,1,2,4,8,12 hours post-AM dose at Week1Day1 and Week3 Day 4; Week1 Day5(0.5, 3 hours post-AM dose); pre-dose, 0.25,0.5,1,2,4,8,12, 36 hours post-PM dose at Week1Day1 and Week3 Day4","title":"Tmax for GSK525762-Part 1 BID","type":"SECONDARY","unitOfMeasure":"Hour"}