{"analyses":[{"groupDescription":"Feasibility will be defined as an enrolled patient receiving the IMRT treatment as planned. It is expected that the treatment will be feasible in at least 90% of patients. If the treatment is feasible in 16 or more out of 20 patients, then the treatment will be declared feasible. If the true feasibility rate is 90%, then there is a 4.3% chance that 15 or fewer feasible patients will be observed.","groupIds":["OG000"],"nonInferiorityComment":"With 20 patients, there is 80% power to detect a difference of 100% with Standard lung RT versus 93% with IMRT assuming a standard deviation of 8 (as seen for the whole heart), a one tailed test and a Bonferroni correction for 4 statistical tests so that each test is done at p\\<0.0125.","nonInferiorityType":"OTHER","otherAnalysisDescription":"Lung-metastases-free survival will be estimated using Kaplan-Meier survival curves (minimum period of six months).","pValue":"<0.0125","pValueComment":"The reported p value was calculated. The statistical analysis performed is attached to the outcome measure reported.","statisticalMethod":"Bonferroni corrected at p<0.0125"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"5.4","value":"96"}]}],"title":"Heart - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.8","value":"100"}]}],"title":"Heart - V50 (%) for AP- PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"12.1","value":"65"}]}],"title":"Heart - V83 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.2","value":"100"}]}],"title":"Heart - V83 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.5","value":"39"}]}],"title":"Heart - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"6.7","value":"97"}]}],"title":"Heart- V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.8","value":"95"}]}],"title":"Left Ventricle - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0","value":"100"}]}],"title":"Left Ventricle - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.9","value":"33"}]}],"title":"Left Ventricle - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"2.7","value":"99"}]}],"title":"Left Ventricle - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.8","value":"91"}]}],"title":"Right Ventricle - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.6","value":"100"}]}],"title":"Right Ventricle - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"12.7","value":"42"}]}],"title":"Right Ventricle - V83 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"4","value":"99"}]}],"title":"Right Ventricle - V83 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.9","value":"18"}]}],"title":"Right Ventricle - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8.2","value":"97"}]}],"title":"Right Ventricle - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.4","value":"99"}]}],"title":"Right Atrium - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.7","value":"99"}]}],"title":"Right Atrium - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"22.5","value":"57"}]}],"title":"Right Atrium - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.1","value":"97"}]}],"title":"Right Atrium - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.4","value":"99"}]}],"title":"Left Atrium V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.2","value":"100"}]}],"title":"Left Atrium V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"22.3","value":"55"}]}],"title":"Left Atrium - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"15.4","value":"94"}]}],"title":"Left Atrium - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0","value":"100"}]}],"title":"Right Coronary Artery - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0","value":"100"}]}],"title":"Right Coronary Artery - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"9.9","value":"88"}]}],"title":"Left Coronary Artery - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"1.3","value":"99"}]}],"title":"Left Coronary Artery - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"8","value":"94"}]}],"title":"Myocardium - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0","value":"100"}]}],"title":"Myocardium - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.56","value":"69"}]}],"title":"Myocardium - V95 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.88","value":"99"}]}],"title":"Myocardium - V95 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"32.5","value":"44"}]}],"title":"Thyroid - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"31.3","value":"33"}]}],"title":"Thyroid - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"7.6","value":"5"}]}],"title":"Kidneys - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"6.8","value":"6"}]}],"title":"Kidneys - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"21.7","value":"62"}]}],"title":"Stomach - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"24.5","value":"62"}]}],"title":"Stomach - V50 (%) for AP-PA"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.4","value":"55"}]}],"title":"Liver - V50 (%) for IMRT"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"11.4","value":"54"}]}],"title":"Liver - V50 (%) for AP-PA"}],"denoms":[{"counts":[{"groupId":"OG000","value":"20"}],"units":"Participants"}],"description":"The IMRT and standard anteroposterior (AP-PA) treatment plans were reviewed and compared for target coverage and organ dose-volume histograms. The mean percentage volume of the organ or organ sub-region receiving a percentage of the dose was estimated from the computerized treatment plans for these two techniques were estimated and compared statistically","dispersionType":"Standard Deviation","groups":[{"description":"Patients undergo cardiac-sparing whole lung intensity-modulated radiation therapy (IMRT).","id":"OG000","title":"Treatment (IMRT)"}],"paramType":"MEAN","reportingStatus":"POSTED","timeFrame":"This outcome is measured from central review of radiation plans within 1-2 days of receipt.","title":"Mean Percentage Radiation Dose to Organ Volumes","type":"SECONDARY","unitOfMeasure":"Mean % radiation dose to % organ volume"}