{"eventGroups":[{"deathsNumAffected":40,"deathsNumAtRisk":460,"description":"experimental group (arm B) M1 scheme\n\nM1 scheme: short course 5 x 5 Gy radiation scheme is followed by six cycles of combination chemotherapy (capecitabine and oxaliplatin (CAPOX)) and surgery. FOLFOX4 may be given as alternative for CAPOX","id":"EG000","otherNumAffected":429,"otherNumAtRisk":460,"seriousNumAffected":31,"seriousNumAtRisk":460,"title":"B: 5x5Gy -> CAPOX -> Surgery"},{"deathsNumAffected":36,"deathsNumAtRisk":441,"description":"control group (arm A) standard long course chemoradiotherapy\n\nstandard long course chemoradiotherapy: long course chemoradiotherapy followed by surgery. Optional adjuvant chemotherapy (CAPOX or FOLFOX) is allowed in the control group.","id":"EG001","otherNumAffected":421,"otherNumAtRisk":441,"seriousNumAffected":13,"seriousNumAtRisk":441,"title":"A: 5 Weeks Chemoradiation -> Surgery"}],"frequencyThreshold":"0","otherEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":429,"numAtRisk":460,"numEvents":429},{"groupId":"EG001","numAffected":421,"numAtRisk":441,"numEvents":421}],"term":"Grade 1-3 AEs"}],"seriousEvents":[{"assessmentType":"NON_SYSTEMATIC_ASSESSMENT","organSystem":"Gastrointestinal disorders","stats":[{"groupId":"EG000","numAffected":31,"numAtRisk":460,"numEvents":31},{"groupId":"EG001","numAffected":13,"numAtRisk":441,"numEvents":13}],"term":"grade 4+5 AEs"}],"timeFrame":"3 years"}