{"analyses":[{"ciLowerLimit":"1.3057","ciNumSides":"TWO_SIDED","ciPctValue":"80","ciUpperLimit":"13.9994","estimateComment":"Based on the Cox proportional hazards model stratified by prognosis stratum according to IVRS.","groupIds":["OG000","OG001"],"nonInferiorityType":"OTHER","pValue":"0.0112","paramType":"Odds Ratio (OR)","paramValue":"4.2755","statisticalMethod":"Cochran-Mantel-Haenszel"}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"12.9","upperLimit":"23.5","value":"18.2"},{"groupId":"OG001","lowerLimit":"0.0","upperLimit":"5.2","value":"2.3"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"88"},{"groupId":"OG001","value":"44"}],"units":"Participants"}],"description":"For AML participants:CR were those with repeat bone marrow showing \\<5% myeloblasts,spicules present and no Auer rods, peripheral blood showing neutrophils\\>=1000/mcL and platelets\\>=100,000/mcL, transfusion independent and no extramedullary disease. For MDS participants:CR were those with repeat bone marrow showing \\<=5% myeloblasts, peripheral blood showing neutrophils\\>=1000/mcL, platelets\\>=100,000/mcL, 0% blast and hemoglobin (Hgb)\\>= 11 g/dL, normal maturation of all cell lines.","dispersionType":"80% Confidence Interval","groups":[{"description":"Participants received oral doses of glasdegib tablets 100 mg QD in 28-day cycles on a continuous basis, starting on Day 1 of Cycle 1. LDAC was given at a dose of 20 mg subcutaneously BID on Days 1-10 of the 28 day cycles.","id":"OG000","title":"Phase 2 Unfit: Glasdegib 100 mg + LDAC"},{"description":"Participants received LDAC subcutaneously at a dose of 20 mg BID on Days 1-10 of the 28 day cycles.","id":"OG001","title":"Phase 2 Unfit: LDAC Alone"}],"paramType":"NUMBER","populationDescription":"Full analysis set: all randomized participants of Phase 2 Unfit arm.","reportingStatus":"POSTED","timeFrame":"4 years","title":"Percentage of Participants With Complete Response (CR) at Phase 2 Unfit","type":"SECONDARY","unitOfMeasure":"Percentage of participants"}