{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"55"}]}],"title":"Baseline, Any bleeding n=87"},{"categories":[{"measurements":[{"groupId":"OG000","value":"17"}]}],"title":"Baseline, Significant bleeding n=87"},{"categories":[{"measurements":[{"groupId":"OG000","value":"29"}]}],"title":"Week 1, Any bleeding n=86"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Week 1, Significant bleeding n=86"},{"categories":[{"measurements":[{"groupId":"OG000","value":"22"}]}],"title":"Week 2, Any bleeding n=85"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 2, Significant bleeding n=85"},{"categories":[{"measurements":[{"groupId":"OG000","value":"20"}]}],"title":"Week 3, Any bleeding n=86"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Week 3, Significant bleeding n=86"},{"categories":[{"measurements":[{"groupId":"OG000","value":"20"}]}],"title":"Week 4, Any bleeding n=68"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Week 4, Significant bleeding n=68"},{"categories":[{"measurements":[{"groupId":"OG000","value":"21"}]}],"title":"Week 5, Any bleeding n=61"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Week 5, Significant bleeding n=61"},{"categories":[{"measurements":[{"groupId":"OG000","value":"17"}]}],"title":"Week 6, Any bleeding n=55"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Week 6, Significant bleeding n=55"},{"categories":[{"measurements":[{"groupId":"OG000","value":"14"}]}],"title":"Week 7, Any bleeding n=52"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Week 7, Significant bleeding n=52"},{"categories":[{"measurements":[{"groupId":"OG000","value":"17"}]}],"title":"Week 8, Any bleeding n=52"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Week 8, Significant bleeding n=52"},{"categories":[{"measurements":[{"groupId":"OG000","value":"11"}]}],"title":"Week 9, Any bleeding n=45"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Week 9, Significant bleeding n=45"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"Week 10, Any bleeding n=42"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 10, Significant bleeding n=42"},{"categories":[{"measurements":[{"groupId":"OG000","value":"12"}]}],"title":"Week 11, Any bleeding n=40"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Week 11, Significant bleeding n=40"},{"categories":[{"measurements":[{"groupId":"OG000","value":"15"}]}],"title":"Week 12, Any bleeding n=63"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Week 12, Significant bleeding n=63"},{"categories":[{"measurements":[{"groupId":"OG000","value":"9"}]}],"title":"Week 13, Any bleeding n=30"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 13, Significant bleeding n=30"},{"categories":[{"measurements":[{"groupId":"OG000","value":"9"}]}],"title":"Week 14, Any bleeding n=38"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 14, Significant bleeding n=38"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10"}]}],"title":"Week 15, Any bleeding n=43"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 15, Significant bleeding n=43"},{"categories":[{"measurements":[{"groupId":"OG000","value":"11"}]}],"title":"Week 16, Any bleeding n=47"},{"categories":[{"measurements":[{"groupId":"OG000","value":"4"}]}],"title":"Week 16, Significant bleeding n=47"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10"}]}],"title":"Week 17, Any bleeding n=37"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 17, Significant bleeding n=37"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"Week 18, Any bleeding n=33"},{"categories":[{"measurements":[{"groupId":"OG000","value":"1"}]}],"title":"Week 18, Significant bleeding n=33"},{"categories":[{"measurements":[{"groupId":"OG000","value":"15"}]}],"title":"Week 19, Any bleeding n=44"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 19, Significant bleeding n=44"},{"categories":[{"measurements":[{"groupId":"OG000","value":"7"}]}],"title":"Week 20, Any bleeding n=39"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 20, Significant bleeding n=39"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10"}]}],"title":"Week 21, Any bleeding n=41"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 21, Significant bleeding n=41"},{"categories":[{"measurements":[{"groupId":"OG000","value":"7"}]}],"title":"Week 22, Any bleeding n=34"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Week 22, Significant bleeding n=34"},{"categories":[{"measurements":[{"groupId":"OG000","value":"15"}]}],"title":"Week 23, Any bleeding n=36"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Week 23, Significant bleeding n=36"},{"categories":[{"measurements":[{"groupId":"OG000","value":"19"}]}],"title":"Week 24, Any bleeding n=79"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Week 24, Significant bleeding n=79"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"Follow-up Week 1, Any bleeding n=29"},{"categories":[{"measurements":[{"groupId":"OG000","value":"2"}]}],"title":"Follow-up Week 1, Significant bleeding n=29"},{"categories":[{"measurements":[{"groupId":"OG000","value":"25"}]}],"title":"Follow-up Week 2, Any bleeding n=37"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Follow-up Week 2, Significant bleeding n=37"},{"categories":[{"measurements":[{"groupId":"OG000","value":"17"}]}],"title":"Follow-up Week 3, Any bleeding n=40"},{"categories":[{"measurements":[{"groupId":"OG000","value":"5"}]}],"title":"Follow-up Week 3, Significant bleeding n=40"},{"categories":[{"measurements":[{"groupId":"OG000","value":"23"}]}],"title":"Follow-up Week 4, Any bleeding n=70"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3"}]}],"title":"Follow-up Week 4, Significant bleeding n=70"},{"categories":[{"measurements":[{"groupId":"OG000","value":"38"}]}],"title":"Any follow-up Week, Any bleeding n=77"},{"categories":[{"measurements":[{"groupId":"OG000","value":"8"}]}],"title":"Any Follow-up Week, Significant bleeding n=77"}],"denoms":[{"counts":[{"groupId":"OG000","value":"87"}],"units":"Participants"}],"description":"The WHO Bleeding Scale is a measure of bleeding severity with the following grades: Grade 0 = no bleeding, Grade 1 = petechiae, Grade 2 = mild blood loss, Grade 3 = gross bleeding and Grade 4 = debilitating blood loss. The WHO Grades were dichotomized into the following categories: no bleeding = Grade 0; any bleeding = Grade 1 to 4; no clinically significant bleeding = Grade 0 to 1; clinically significant bleeding = Grade 2 to 4.","groups":[{"description":"Participants who received eltrombopag in Part 1 continued on the same dose in Part 2 unless adjustments were warranted according to the dosing guidelines. Participants who received placebo in Part 1 received Eltrombopag as per age criteria as follows: aged between 6 and 17 years with a body weight \\<27 kg received eltrombopag 37.5 mg QD, and those with a body weight \\>=27 kg received eltrombopag 50 mg QD. Participants of East Asian ancestry received a starting dose of eltrombopag 25 mg QD. Participants aged between 1 and 5 years received eltrombopag 1.2 mg/kg QD and; participants of East Asian ancestry received a starting dose of eltrombopag 0.8 mg/kg/day.","id":"OG000","title":"Part 2 (Open-Label Period) - Eltrombopag"}],"paramType":"NUMBER","populationDescription":"ITT Population. Only those participants who entered into Part 2 open-label Eltrombopag only phase were analyzed. Only those participants available at the specified time points were analyzed (represented by n=X in the category titles).","reportingStatus":"POSTED","timeFrame":"From Baseline of Part 2 through Follow-up","title":"Number of Participants With Any Bleeding and Significant Bleeding as Assessed Using the WHO Bleeding Scale During Part 2","type":"SECONDARY","unitOfMeasure":"Participants"}