{"analyses":[{"ciLowerLimit":"8.15","ciNumSides":"TWO_SIDED","ciPctValue":"95","ciUpperLimit":"78.73","groupIds":["OG000","OG001"],"nonInferiorityType":"SUPERIORITY_OR_OTHER","pValue":"<0.001","paramType":"Odds Ratio (OR)","paramValue":"25.33","statisticalComment":"Repeated measures model for binary data using Generalized linear mixed model","statisticalMethod":"Repeated measures model for binary data","testedNonInferiority":false}],"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"15.9"}]}],"title":"Week 1"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3.4"},{"groupId":"OG001","value":"23.8"}]}],"title":"Week 2"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"},{"groupId":"OG001","value":"31.7"}]}],"title":"Week 3"},{"categories":[{"measurements":[{"groupId":"OG000","value":"6.9"},{"groupId":"OG001","value":"36.5"}]}],"title":"Week 4"},{"categories":[{"measurements":[{"groupId":"OG000","value":"6.9"},{"groupId":"OG001","value":"47.6"}]}],"title":"Week 5"},{"categories":[{"measurements":[{"groupId":"OG000","value":"6.9"},{"groupId":"OG001","value":"38.1"}]}],"title":"Week 6"},{"categories":[{"measurements":[{"groupId":"OG000","value":"10.3"},{"groupId":"OG001","value":"44.4"}]}],"title":"Week 7"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3.4"},{"groupId":"OG001","value":"44.4"}]}],"title":"Week 8"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3.4"},{"groupId":"OG001","value":"42.9"}]}],"title":"Week 9"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3.4"},{"groupId":"OG001","value":"52.4"}]}],"title":"Week 10"},{"categories":[{"measurements":[{"groupId":"OG000","value":"6.9"},{"groupId":"OG001","value":"49.2"}]}],"title":"Week 11"},{"categories":[{"measurements":[{"groupId":"OG000","value":"3.4"},{"groupId":"OG001","value":"58.7"}]}],"title":"Week 12"}],"denoms":[{"counts":[{"groupId":"OG000","value":"29"},{"groupId":"OG001","value":"63"}],"units":"Participants"}],"description":"Percentage of participants who responded (defined as platelet count \\>= 50 Gi/L in absence of rescue) at least once up to week 12 of Part 1 (Odds of achieving a platelet count \\>=50 Gi/L during the first 12 weeks of Part 1)","groups":[{"description":"In Part 1, participants aged between 6 and 17 years with a body weight \\<27 kg received placebo 37.5 mg QD, and those with a body weight \\>=27 kg received placebo 50 mg QD. Participants of East Asian ancestry received a starting dose of placebo 25 mg QD. Participants aged between 1 and 5 years received placebo 1.2 mg/kg QD; participants of East Asian ancestry received a starting dose of placebo 0.8 mg/kg/day.","id":"OG000","title":"Part 1 (Randomized Period)-Placebo"},{"description":"In Part 1, participants aged between 6 and 17 years with a body weight \\<27 kg received eltrombopag 37.5 mg QD, and those with a body weight \\>=27 kg received eltrombopag 50 mg QD. Participants of East Asian ancestry received a starting dose of eltrombopag 25 mg QD. Participants aged between 1 and 5 years received eltrombopag 1.2 mg/kg QD; participants of East Asian ancestry received a starting dose of eltrombopag 0.8 mg/kg/day.","id":"OG001","title":"Part 1 (Randomized Period) - Eltrombopag"}],"paramType":"NUMBER","populationDescription":"ITT Population","reportingStatus":"POSTED","timeFrame":"From Week 1 up to Week 12 of Part 1","title":"Percentage of Responders","type":"SECONDARY","unitOfMeasure":"Percentage of participants"}