{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"16","upperLimit":"37","value":"19"}]}],"title":"Neutrophil Engraftment"},{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"10","upperLimit":"47","value":"14"}]}],"title":"Platelet Engraftment"}],"denoms":[{"counts":[{"groupId":"OG000","value":"43"}],"units":"Participants"}],"description":"Descriptive statistics will be used to assess the median days of neutrophil and platelet recovery. The day of neutrophil recovery is defined as the first day of three consecutive lab values on different days, after the conditioning regimen-induced nadir of blood counts, that the absolute neutrophil count is \\> 500/uL. The day of platelet recovery is defined as the first day of three consecutive lab values on different days, after the conditioning regimen-induced nadir of blood counts, that the platelet count is \\>= 20,000/uL without platelet transfusion support in the seven days prior.","dispersionType":"Full Range","groups":[{"description":"PREPARATIVE REGIMEN: Patients receive TBI BID on days -4 or -3 to -1. Some patients also receive fludarabine IV daily on days -5 to -2 and busulfan IV over 3 hours QD or over 2 hours every 6 hours on days -5 to -2. Patients may also undergo CNS prophylaxis, testicular irradiation, and/or involved field irradiation as per standard practice.\n\nTRANSPLANTATION: Patients undergo allogeneic PBSCT on day 0 per standard practice.\n\nGVHD PROPHYLAXIS: Patients receive cyclophosphamide IV over 1-2 hours on days 3-4. Patients also receive cyclosporine IV every 12 hours or every 8 hours beginning on day 5 with taper on days 56-126.\n\ncyclophosphamide: Given IV\n\ncyclosporine: Given IV\n\nperipheral blood stem cell transplantation: Undergo allogeneic PBSCT\n\ntotal-body irradiation: Undergo TBI\n\nfludarabine phosphate: Given IV\n\nbusulfan: Given IV\n\nallogeneic hematopoietic stem cell transplantation: Undergo allogeneic PBSCT","id":"OG000","title":"Treatment (TBI, PBSCT, and Cyclophosphamide GVHD Prophylaxis)"}],"paramType":"MEDIAN","reportingStatus":"POSTED","timeFrame":"Up to day +100","title":"Hematologic Recovery","type":"SECONDARY","unitOfMeasure":"days"}