{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","lowerLimit":"1.0","upperLimit":"1.4","value":"1.1"},{"comment":"Upper confidence limit could not be estimated due to low number of patients with an event.","groupId":"OG001","lowerLimit":"0.7","upperLimit":"NA","value":"2.1"},{"groupId":"OG002","lowerLimit":"1.4","upperLimit":"11.1","value":"8.4"},{"groupId":"OG003","lowerLimit":"4.1","upperLimit":"25.8","value":"15.9"},{"comment":"Upper confidence limit could not be estimated due to low number of patients with an event.","groupId":"OG004","lowerLimit":"5.1","upperLimit":"NA","value":"33.2"}]}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"31"},{"groupId":"OG001","value":"4"},{"groupId":"OG002","value":"18"},{"groupId":"OG003","value":"21"},{"groupId":"OG004","value":"17"}],"units":"Participants"}],"description":"Time to Progression (Kaplan Meier estimate)","dispersionType":"95% Confidence Interval","groups":[{"description":"Treatment cycle 28 days, MOR03087 doses applied day 1 \\& 15, initial 0.01 mg/kg, max 16 mg/kg","id":"OG000","title":"Part A: MOR03087 Biweekly Dose Escalation"},{"description":"Treatment cycle 28 days, MOR03087 doses applied day 1, 8, 15 \\& 22 plus extra dose on day 4 of cycle 1, Initial MOR03087 dose 4 mg/kg, max 16 mg/kg","id":"OG001","title":"Part B: MOR03087 Weekly Dose Escalation"},{"description":"Treatment cycle 28 days, iv MOR03087 and oral dexamethasone (DEX) applied day 1, 8, 15 \\& 22 plus extra dose on day 4 of cycle 1, initial MOR03087 dose 4 mg/kg, max 16 mg/kg. DEX dose 40 mg (≤ 75 years old) or 20 mg (\\> 75 years old)","id":"OG002","title":"Part C: MOR03087 Plus Dexamethasone"},{"description":"Treatment cycle 28 days, iv MOR03087 and oral dexamethasone (DEX) applied day 1, 8, 15 \\& 22 plus extra dose on day 4 of cycle 1, initial MOR03087 dose 8 mg/kg, max 16 mg/kg. DEX dose 40 mg (≤ 75 years old) or 20 mg (\\> 75 years old). Pomalidomide was administered to patients orally 4 mg on days 1-21 of the 28-day cycle.","id":"OG003","title":"Part D: MOR03087 Plus Pomalidomide + Dexamethasone"},{"description":"Treatment cycle 28 days, iv MOR03087 and oral dexamethasone (DEX) applied day 1, 8, 15 \\& 22 plus extra dose on day 4 of cycle 1, initial MOR03087 dose 8 mg/kg, max 16 mg/kg. DEX dose 40 mg (≤ 75 years old) or 20 mg (\\> 75 years old).\n\nLenalidomide was administered to patients orally 25 mg on days 1-21 of the 28-day cycle.","id":"OG004","title":"Part E: MOR03087 Plus Lenalidomide + Dexamethasone"}],"paramType":"MEDIAN","populationDescription":"safety population","reportingStatus":"POSTED","timeFrame":"patients were observed for up to 36 months","title":"Time to Progression","type":"SECONDARY","unitOfMeasure":"months"}