{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"7"}],"units":"Participants"}],"title":"Supermobilizers"},{"categories":[{"measurements":[{"groupId":"OG000","value":"0"}]}],"denoms":[{"counts":[{"groupId":"OG000","value":"17"}],"units":"Participants"}],"title":"Normal Mobilizers"}],"denoms":[{"counts":[{"groupId":"OG000","value":"24"}],"units":"Participants"}],"description":"Number of participants that needed remobilization in supermobilizers and normal mobilizers.\n\nRemobilization can be described as follows:\n\nThe first step for patients undergoing autologous hematopoietic cell transplantation is to mobilize hematopoietic progenitor/stem cells from the bone marrow using G-CSF, plerixafor and/or chemotherapy. This is followed by collection of the cells by apheresis. If sufficient number of progenitor/stem cells cannot be mobilized and then collected by apheresis to proceed with transplantation, it is considered as \"mobilization failure\". For these patients, mobilization of their hematopoietic progenitor/stem cells is attempted a second time (\"remobilization\"). The need to do a second 'mobilization' attempt is not ideal.","groups":[{"description":"Patients receive etoposide IV over 4 hours on day 0, filgrastim SC QD beginning day 1, and plerixafor SC 15-18 hours prior to apheresis. Patients unable to achieve target collection of \\>= 8 x 10\\^6 CD34+ cells/kg receive another dose of plerixafor followed by apheresis. Following the second apheresis, patients achieving =\\< 2 x 10\\^6 CD34+ cells/kg may continue filgrastim with plerixafor and continue collection according to the attending physician.\n\nplerixafor: Given SC\n\nfilgrastim: Given SC\n\netoposide: Given IV\n\nleukapheresis: Undergo apheresis","id":"OG000","title":"Treatment (Stem Cell Supermobilization)"}],"paramType":"COUNT_OF_PARTICIPANTS","populationDescription":"Participants that were mobilized","reportingStatus":"POSTED","timeFrame":"Up to 28 days post treatment","title":"Need for Remobilization","type":"SECONDARY","unitOfMeasure":"Participants"}